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Study · Measured the body's own peptide · 2014

1 result

MDMA enhances emotional empathy and prosocial behavior.

Hysek CM, Schmid Y, Simmler LD, Domes G, Heinrichs M, Eisenegger C, Preller KH, Quednow BB, Liechti ME

Social cognitive and affective neuroscience4 Oct 2013Cited by 252 (Europe PMC)

PMID24097374 (opens in a new tab)PMCIDPMC4221206 (opens in a new tab)DOI10.1093/scan/nst161 (opens in a new tab)PepBankPUB-24097374
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelRandomized controlled trialOther

    In healthy volunteers, MDMA increased plasma levels of the body's own oxytocin versus placebo.

    In plain wordsIn healthy volunteers, MDMA raised the body's own oxytocin levels in blood compared with placebo.

    Peptide
    Oxytocin
    Outcome
    IncreasePlasma oxytocin after MDMA
    Study

    n = 32

    Comparator
    Placebo
    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Source sentences

    Summary
    MDMA increased plasma levels of cortisol and prolactin, which are markers of serotonergic and noradrenergic activity, and of oxytocin, which has been associated with prosocial behavior.
    1 context sentence
    Summary · context
    We also assessed effects of MDMA on plasma levels of hormones involved in social behavior using a placebo-controlled, double-blind, random-order, cross-over design in 32 healthy volunteers (16 women).

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:51 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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