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Study · Randomized controlled trial · n = 69 · 2014

3 results

Oxytocin differentially modulates compromise and competitive approach but not withdrawal to antagonists from own vs. rivaling other groups.

Ten Velden FS, Baas M, Shalvi S, Kret ME, De Dreu CK

Brain research20 Sept 2013Cited by 17 (Europe PMC)

PMID24055737 (opens in a new tab)DOI10.1016/j.brainres.2013.09.013 (opens in a new tab)PepBankPUB-24055737
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In healthy men playing a poker game, oxytocin increased settling with an in-group compared with an out-group antagonist; this was not seen under placebo.

    In plain wordsIn healthy men, oxytocin made them settle more with players from their own group than with outsiders, unlike placebo.

    Peptide
    Oxytocin
    Outcome
    IncreaseCompromise (settling) toward in-group versus out-group antagonist
    Study

    n = 69

    Comparator
    Placebo (in-group versus out-group antagonist)
    Outcome group
    Social behavior and cognition · Mental health and mood
    Studied dose
    24 IUAs given in this study (human).

    Source sentences

    Summary
    Under placebo, participants withdrew and competed depending on their own (low vs. high) competitive strength, regardless of their antagonist's group membership. Under oxytocin, however, participants settled more and competed less with an in-group as compared to an out-group antagonist; withdrawal wa…
    1 context sentence
    Summary · context
    Here we examined decision making in an incentivized two-player poker game with either an in-group or out-group antagonist. Sixty nine healthy males received 24 IU oxytocin or matching placebo, and played four rounds of a simplified poker game.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In healthy men playing a poker game, oxytocin reduced competing with an in-group compared with an out-group antagonist.

    In plain wordsIn healthy men, oxytocin made them compete less with players from their own group than with outsiders.

    Peptide
    Oxytocin
    Outcome
    DecreaseCompetitive approach toward in-group versus out-group antagonist
    Study

    n = 69

    Comparator
    Placebo (in-group versus out-group antagonist)
    Outcome group
    Social behavior and cognition · Mental health and mood
    Studied dose
    24 IUAs given in this study (human).

    Source sentences

    Summary
    Under oxytocin, however, participants settled more and competed less with an in-group as compared to an out-group antagonist; withdrawal was unaffected by group membership.
    1 context sentence
    Summary · context
    Here we examined decision making in an incentivized two-player poker game with either an in-group or out-group antagonist. Sixty nine healthy males received 24 IU oxytocin or matching placebo, and played four rounds of a simplified poker game.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In healthy men playing a poker game, withdrawal was unaffected by antagonist group membership under oxytocin.

    In plain wordsIn healthy men on oxytocin, giving up in the game did not depend on whether the opponent was in their own group.

    Peptide
    Oxytocin
    Outcome
    No significant changeWithdrawal by antagonist group membership
    Study

    n = 69

    Comparator
    Placebo (in-group versus out-group antagonist)
    Outcome group
    Social behavior and cognition · Mental health and mood
    Studied dose
    24 IUAs given in this study (human).

    Source sentences

    Summary
    withdrawal was unaffected by group membership.
    1 context sentence
    Summary · context
    Here we examined decision making in an incentivized two-player poker game with either an in-group or out-group antagonist. Sixty nine healthy males received 24 IU oxytocin or matching placebo, and played four rounds of a simplified poker game.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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