Skip to content

Study · In vitro (cells) · escherichia coli and streptococcus pyogenes · 2013

2 results

Oxygen deprivation affects the antimicrobial action of LL-37 as determined by microplate real-time kinetic measurements under anaerobic conditions.

Eini A, Sol A, Coppenhagen-Glazer S, Skvirsky Y, Zini A, Bachrach G

Anaerobe8 May 2013Cited by 15 (Europe PMC)

PMID23664904 (opens in a new tab)DOI10.1016/j.anaerobe.2013.04.014 (opens in a new tab)PepBankPUB-23664904
Publisher pagePubMedAsk about this study
Jump to 2 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Activity measurement

    E. coli was more sensitive to LL‑37 under anaerobic than under aerobic conditions.

    In plain wordsIn lab tests, E. coli was more sensitive to LL‑37 without oxygen than with oxygen.

    Peptide
    LL-37
    Outcome
    IncreaseE. coli sensitivity to LL-37 under anaerobiosis
    Study

    Escherichia colin: not reported in source

    Bacterial culture in microplates
    Comparator
    Aerobic conditions
    Outcome group
    Infection and antimicrobial activity · Infection
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The oxygen facultative E. coli grew to a higher density under aerobic conditions and its sensitivity to LL-37 was increased under anaerobiosis.
    2 context sentences
    Summary · context
    In order to test the effect of oxygen (or lack thereof) on LL-37's activity against E. coli and S. pyogenes, a method for adapting commonly used microtiter plates for real-time growth-kinetic (and growth-inhibition) measurements under anaerobic conditions was developed.
    Summary · context
    The sensitivities of E. coli and S. pyogenes to LL-37 were tested under anaerobic conditions and compared to those in aerobic ones.
  2. 02LabIn vitro (cells)Activity measurement

    S. pyogenes was much more resistant to LL‑37 under oxygen deprivation than under aerobic conditions.

    In plain wordsIn lab tests, S. pyogenes was much more resistant to LL‑37 without oxygen than with oxygen.

    Peptide
    LL-37
    Outcome
    DecreaseS. pyogenes sensitivity to LL-37 under oxygen deprivation
    Study

    Streptococcus pyogenesn: not reported in source

    Bacterial culture in microplates
    Comparator
    Aerobic conditions
    Outcome group
    Infection and antimicrobial activity · Infection
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The microaerophilic pathogen S. pyogenes grew faster and to a higher density under anaerobic conditions and was much more resistant to LL-37 under oxygen deprivation.
    2 context sentences
    Summary · context
    In order to test the effect of oxygen (or lack thereof) on LL-37's activity against E. coli and S. pyogenes, a method for adapting commonly used microtiter plates for real-time growth-kinetic (and growth-inhibition) measurements under anaerobic conditions was developed.
    Summary · context
    The sensitivities of E. coli and S. pyogenes to LL-37 were tested under anaerobic conditions and compared to those in aerobic ones.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    11 Oct 2026, 00:50 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:58 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.