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Study · Not a test of the peptide alone · 2013

8 results

[Delta-sleep inducing peptide entrapment and release from polymer hydrogels based on modified polyvinyl alcohol in vitro].

Sukhanova TV, Artiukhov AA, Prudchenko IA, Golunova AS, Seminikhina MA, Shtil'man MI, Markvicheva EA

Biomeditsinskaia khimiia1 Jan 2013Cited by 1 (Europe PMC)

PMID23650723 (opens in a new tab)DOI10.18097/pbmc20135901065 (opens in a new tab)PepBankPUB-23650723
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study8

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone8

In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Delta sleep-inducing peptide (DSIP).

  1. 01LabNot a test of Delta sleep-inducing peptide (DSIP) aloneIn vitro (cell-free)Other

    In an in vitro model, 74% of DSIP was released in water after 30 min from a macroporous poly(vinyl alcohol) hydrogel.

    In plain wordsIn lab tests, a macroporous hydrogel released 74% of the loaded DSIP into water within 30 minutes.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableDSIP release from macroporous PVA hydrogel in water at 30 min
    Study

    n: not reported in source

    poly(vinyl alcohol)-based hydrogels, in vitro release
    Outcome group
    Formulation, delivery and stability · Pharmacology

    Measurements

    peptide release at 30 min
    74%
    water

    Source sentences

    Summary
    DSIP release from the macroporous PVA hydrogel after 30 min incubation was 74, 70 and 64% in water, PBS and 0.9% NaCl, relatively

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  2. 02LabNot a test of Delta sleep-inducing peptide (DSIP) aloneIn vitro (cell-free)Other

    In an in vitro model, 70% of DSIP was released in PBS after 30 min from a macroporous poly(vinyl alcohol) hydrogel.

    In plain wordsIn lab tests, a macroporous hydrogel released 70% of the loaded DSIP into PBS within 30 minutes.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableDSIP release from macroporous PVA hydrogel in PBS at 30 min
    Study

    n: not reported in source

    poly(vinyl alcohol)-based hydrogels, in vitro release
    Outcome group
    Formulation, delivery and stability · Pharmacology

    Measurements

    peptide release at 30 min
    70%
    PBS

    Source sentences

    Summary
    DSIP release from the macroporous PVA hydrogel after 30 min incubation was 74, 70 and 64% in water, PBS and 0.9% NaCl, relatively

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  3. 03LabNot a test of Delta sleep-inducing peptide (DSIP) aloneIn vitro (cell-free)Other

    In an in vitro model, 64% of DSIP was released in 0.9% NaCl after 30 min from a macroporous poly(vinyl alcohol) hydrogel.

    In plain wordsIn lab tests, a macroporous hydrogel released 64% of the loaded DSIP into saline within 30 minutes.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableDSIP release from macroporous PVA hydrogel in 0.9% NaCl at 30 min
    Study

    n: not reported in source

    poly(vinyl alcohol)-based hydrogels, in vitro release
    Outcome group
    Formulation, delivery and stability · Pharmacology

    Measurements

    peptide release at 30 min
    64%
    0.9% NaCl

    Source sentences

    Summary
    DSIP release from the macroporous PVA hydrogel after 30 min incubation was 74, 70 and 64% in water, PBS and 0.9% NaCl, relatively

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  4. 04LabNot a test of Delta sleep-inducing peptide (DSIP) aloneIn vitro (cell-free)Other

    In an in vitro model, DSIP release from the macroporous poly(vinyl alcohol) hydrogel was completed in 3 hs.

    In plain wordsIn lab tests, the macroporous hydrogel released all of the DSIP within 3 hours.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableTime to complete DSIP release from macroporous PVA hydrogel
    Study

    n: not reported in source

    poly(vinyl alcohol)-based hydrogels, in vitro release
    Outcome group
    Formulation, delivery and stability · Pharmacology

    Measurements

    time to complete release
    3 hs
    macroporous PVA hydrogel

    Source sentences

    Summary
    and it was completed in 3 hs.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  5. 05LabNot a test of Delta sleep-inducing peptide (DSIP) aloneIn vitro (cell-free)Other

    In an in vitro model, no DSIP and no degradation products were released from the isotropic hydrogel even after 48 hs of incubation.

    In plain wordsIn lab tests, an isotropic hydrogel released no DSIP even after 48 hours.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    No significant changeDSIP release from isotropic PVA hydrogel
    Study

    n: not reported in source

    poly(vinyl alcohol)-based hydrogels, in vitro release
    Outcome group
    Formulation, delivery and stability · Pharmacology

    Measurements

    incubation time without release
    48 hs
    isotropic hydrogel

    Source sentences

    Summary
    From the isotropic hydrogel the release neither peptide nor products of its degradation was not observed even after 48 hs of incubation.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  6. 06LabNot a test of Delta sleep-inducing peptide (DSIP) aloneIn vitro (cell-free)Other

    In an in vitro model, release of DSIP from freshly prepared hydrogel was 27 and 78% at 30 and 33 hs, respectively.

    In plain wordsIn lab tests, a freshly prepared hydrogel released 27% and then 78% of the DSIP at two time points.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableDSIP release from freshly prepared hydrogel
    Study

    n: not reported in source

    poly(vinyl alcohol)-based hydrogels, in vitro release
    Outcome group
    Formulation, delivery and stability · Pharmacology

    Source sentences

    Summary
    For freshly prepared hydrogel the release kinetics was as follows: 27 and 78% in 30 and 33 hs, relatively.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  7. 07LabNot a test of Delta sleep-inducing peptide (DSIP) aloneIn vitro (cell-free)Other

    In an in vitro model, 63% of DSIP was released within 30 min from lyophilized hydrogel samples.

    In plain wordsIn lab tests, freeze-dried hydrogel samples released 63% of the DSIP within 30 minutes.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableDSIP release from lyophilized hydrogel at 30 min
    Study

    n: not reported in source

    poly(vinyl alcohol)-based hydrogels, in vitro release
    Outcome group
    Formulation, delivery and stability · Pharmacology

    Measurements

    peptide release at 30 min
    63%
    lyophilized hydrogel

    Source sentences

    Summary
    In the case of the lyophilized hydrogel samples the peptide release was 63% in 30 min incubation

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  8. 08LabNot a test of Delta sleep-inducing peptide (DSIP) aloneIn vitro (cell-free)Other

    In an in vitro model, drying hydrogel patterns at room temperature for 3 days resulted in significant DSIP loss because of structure damage.

    In plain wordsIn lab tests, drying the hydrogel at room temperature for 3 days caused major DSIP loss through structural damage.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreasePeptide loss after drying hydrogel at room temperature
    Study

    n: not reported in source

    poly(vinyl alcohol)-based hydrogels, in vitro release
    Outcome group
    Formulation, delivery and stability · Pharmacology

    Source sentences

    Summary
    while drying patterns at room temperature for 3 days resulted in significant peptide loss because its structure damage.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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