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Study · Not a test of the peptide alone · 2013

6 results

In vitro cytocompatibility evaluation of MGF-Ct24E chemically grafted and physically blended with maleic anhydride modified poly(D, L-lactic acid).

Li Y, Wang Y, Wang P, Zhang B, Yan W, Sun J, Pan J

Journal of biomaterials science. Polymer edition11 Sept 2012Cited by 3 (Europe PMC)

PMID23594073 (opens in a new tab)DOI10.1080/09205063.2012.723957 (opens in a new tab)PepBankPUB-23594073
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study6

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone6

In this study, MGF / PEG-MGF was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking MGF / PEG-MGF.

  1. 01LabNot a test of MGF / PEG-MGF aloneIn vitro (cells)Activity measurement

    In rat calvarial osteoblasts, films with MGF-Ct24E grafted or blended into MPLA promoted cell adhesion compared with MPLA alone.

    In plain wordsIn cells, polymer films carrying an MGF fragment helped rat bone cells stick better than the plain polymer film.

    Peptide
    MGF / PEG-MGF
    Outcome
    IncreaseOsteoblast adhesion
    Study

    ratn: not reported in source

    Rat calvarial osteoblasts on polymer films
    Comparator
    MPLA control film
    Outcome group
    Bone and joint · Musculoskeletal

    Source sentences

    Summary
    The results revealed that compared with MPLA, MGF-Ct24E-MPLA, and MGF-Ct24E/MPLA blends promoted adhesion, spreading, proliferation, and the later differentiation and mineralization process of rat calvarial osteoblasts.
    2 context sentences
    Summary · context
    In this study, we evaluated the cytocompatibility of MGF-Ct24E chemically grafted and physically blended with maleic anhydride modified PDLLA, relative to maleic anhydride modified PDLLA (MPLA) as the control.
    Summary · context
    Rat calvarial osteoblasts were seeded on the three polymer films, and cell adhesion, spreading, and proliferation were assessed with an inverted microscope, laser scanning confocal microscope, and a cell counting kit-8, respectively.

    In this study, MGF / PEG-MGF was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking MGF / PEG-MGF.

  2. 02LabNot a test of MGF / PEG-MGF aloneIn vitro (cells)Activity measurement

    In rat calvarial osteoblasts, films with MGF-Ct24E grafted or blended into MPLA promoted cell spreading compared with MPLA alone.

    In plain wordsIn cells, polymer films carrying an MGF fragment helped rat bone cells spread more than the plain polymer film.

    Peptide
    MGF / PEG-MGF
    Outcome
    IncreaseOsteoblast spreading
    Study

    ratn: not reported in source

    Rat calvarial osteoblasts on polymer films
    Comparator
    MPLA control film
    Outcome group
    Bone and joint · Musculoskeletal

    Source sentences

    Summary
    The results revealed that compared with MPLA, MGF-Ct24E-MPLA, and MGF-Ct24E/MPLA blends promoted adhesion, spreading, proliferation, and the later differentiation and mineralization process of rat calvarial osteoblasts.
    2 context sentences
    Summary · context
    In this study, we evaluated the cytocompatibility of MGF-Ct24E chemically grafted and physically blended with maleic anhydride modified PDLLA, relative to maleic anhydride modified PDLLA (MPLA) as the control.
    Summary · context
    Rat calvarial osteoblasts were seeded on the three polymer films, and cell adhesion, spreading, and proliferation were assessed with an inverted microscope, laser scanning confocal microscope, and a cell counting kit-8, respectively.

    In this study, MGF / PEG-MGF was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking MGF / PEG-MGF.

  3. 03LabNot a test of MGF / PEG-MGF aloneIn vitro (cells)Activity measurement

    In rat calvarial osteoblasts, films with MGF-Ct24E grafted or blended into MPLA promoted cell proliferation compared with MPLA alone.

    In plain wordsIn cells, polymer films carrying an MGF fragment helped rat bone cells multiply more than the plain polymer film.

    Peptide
    MGF / PEG-MGF
    Outcome
    IncreaseOsteoblast proliferation
    Study

    ratn: not reported in source

    Rat calvarial osteoblasts on polymer films
    Comparator
    MPLA control film
    Outcome group
    Bone and joint · Musculoskeletal

    Source sentences

    Summary
    The results revealed that compared with MPLA, MGF-Ct24E-MPLA, and MGF-Ct24E/MPLA blends promoted adhesion, spreading, proliferation, and the later differentiation and mineralization process of rat calvarial osteoblasts.
    2 context sentences
    Summary · context
    In this study, we evaluated the cytocompatibility of MGF-Ct24E chemically grafted and physically blended with maleic anhydride modified PDLLA, relative to maleic anhydride modified PDLLA (MPLA) as the control.
    Summary · context
    Rat calvarial osteoblasts were seeded on the three polymer films, and cell adhesion, spreading, and proliferation were assessed with an inverted microscope, laser scanning confocal microscope, and a cell counting kit-8, respectively.

    In this study, MGF / PEG-MGF was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking MGF / PEG-MGF.

  4. 04LabNot a test of MGF / PEG-MGF aloneIn vitro (cells)Activity measurement

    In rat calvarial osteoblasts, films with MGF-Ct24E grafted or blended into MPLA promoted later differentiation compared with MPLA alone.

    In plain wordsIn cells, polymer films carrying an MGF fragment helped rat bone cells mature more than the plain polymer film.

    Peptide
    MGF / PEG-MGF
    Outcome
    IncreaseOsteoblast differentiation (alkaline phosphatase activity)
    Study

    ratn: not reported in source

    Rat calvarial osteoblasts on polymer films
    Comparator
    MPLA control film
    Outcome group
    Bone and joint · Musculoskeletal

    Source sentences

    Summary
    The alkaline phosphatase activity and extracellular calcium production were exploited to characterize the differentiation and mineralization of rat calvarial osteoblasts on various polymer films.
    3 context sentences
    Summary · context
    The results revealed that compared with MPLA, MGF-Ct24E-MPLA, and MGF-Ct24E/MPLA blends promoted adhesion, spreading, proliferation, and the later differentiation and mineralization process of rat calvarial osteoblasts.
    Summary · context
    In this study, we evaluated the cytocompatibility of MGF-Ct24E chemically grafted and physically blended with maleic anhydride modified PDLLA, relative to maleic anhydride modified PDLLA (MPLA) as the control.
    Summary · context
    Rat calvarial osteoblasts were seeded on the three polymer films, and cell adhesion, spreading, and proliferation were assessed with an inverted microscope, laser scanning confocal microscope, and a cell counting kit-8, respectively.

    In this study, MGF / PEG-MGF was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking MGF / PEG-MGF.

  5. 05LabNot a test of MGF / PEG-MGF aloneIn vitro (cells)Activity measurement

    In rat calvarial osteoblasts, films with MGF-Ct24E grafted or blended into MPLA promoted the mineralization process compared with MPLA alone.

    In plain wordsIn cells, polymer films carrying an MGF fragment helped rat bone cells form mineral more than the plain polymer film.

    Peptide
    MGF / PEG-MGF
    Outcome
    IncreaseOsteoblast mineralization (extracellular calcium)
    Study

    ratn: not reported in source

    Rat calvarial osteoblasts on polymer films
    Comparator
    MPLA control film
    Outcome group
    Bone and joint · Musculoskeletal

    Source sentences

    Summary
    The alkaline phosphatase activity and extracellular calcium production were exploited to characterize the differentiation and mineralization of rat calvarial osteoblasts on various polymer films.
    3 context sentences
    Summary · context
    The results revealed that compared with MPLA, MGF-Ct24E-MPLA, and MGF-Ct24E/MPLA blends promoted adhesion, spreading, proliferation, and the later differentiation and mineralization process of rat calvarial osteoblasts.
    Summary · context
    In this study, we evaluated the cytocompatibility of MGF-Ct24E chemically grafted and physically blended with maleic anhydride modified PDLLA, relative to maleic anhydride modified PDLLA (MPLA) as the control.
    Summary · context
    Rat calvarial osteoblasts were seeded on the three polymer films, and cell adhesion, spreading, and proliferation were assessed with an inverted microscope, laser scanning confocal microscope, and a cell counting kit-8, respectively.

    In this study, MGF / PEG-MGF was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking MGF / PEG-MGF.

  6. 06LabNot a test of MGF / PEG-MGF aloneIn vitro (cells)Activity measurement

    In rat calvarial osteoblasts, the positive effect of the chemically grafted MGF-Ct24E-MPLA film lasted longer than that of the MGF-Ct24E/MPLA blend.

    In plain wordsIn cells, the effect of the grafted film lasted longer than the effect of the blended film.

    Peptide
    MGF / PEG-MGF
    Outcome
    IncreaseDuration of effect, grafted versus blended film
    Study

    ratn: not reported in source

    Rat calvarial osteoblasts on polymer films
    Comparator
    MGF-Ct24E/MPLA blend
    Outcome group
    Bone and joint · Musculoskeletal

    Source sentences

    Summary
    In addition, the positive effect of MGF-Ct24E-MPLA on rat calvarial osteoblasts was maintained longer than the MGF-Ct24E/MPLA blends.
    2 context sentences
    Summary · context
    In this study, we evaluated the cytocompatibility of MGF-Ct24E chemically grafted and physically blended with maleic anhydride modified PDLLA, relative to maleic anhydride modified PDLLA (MPLA) as the control.
    Summary · context
    Rat calvarial osteoblasts were seeded on the three polymer films, and cell adhesion, spreading, and proliferation were assessed with an inverted microscope, laser scanning confocal microscope, and a cell counting kit-8, respectively.

    In this study, MGF / PEG-MGF was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking MGF / PEG-MGF.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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