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Study · Randomized controlled trial · n = 42 · 2013

2 results

When two become one: the role of oxytocin in interpersonal coordination and cooperation.

Arueti M, Perach-Barzilay N, Tsoory MM, Berger B, Getter N, Shamay-Tsoory SG

Journal of cognitive neuroscience11 Apr 2013Cited by 47 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In 42 participants in a crossover design, oxytocin improved paired performance up to the level of individual performance, whereas performance in pairs was worse than alone after placebo.

    In plain wordsIn 42 people, oxytocin raised performance in pairs up to the level of working alone. After placebo, pairs did worse than individuals.

    Peptide
    Oxytocin
    Outcome
    IncreasePaired performance in a cooperative drawing task
    Study

    n = 42

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Mental health and mood
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The data indicate that following placebo administration, participants performed better alone than in pairs. Yet, the administration of oxytocin improved paired performance up to the level of individual performance.
    2 context sentences
    Summary · context
    Cooperation was assessed using a novel computerized drawing task that may be performed individually or cooperatively by two participants who coordinate their actions.
    Summary · context
    Using a within-subject crossover design, 42 participants performed the task alone and with a partner following the administration of placebo and oxytocin 1 week apart.
  2. 02HumanRandomized controlled trialOther

    In 42 participants, the effect of oxytocin on paired performance depended on the personality traits of cooperativeness or competitiveness.

    In plain wordsIn 42 people, how much oxytocin helped paired performance depended on how cooperative or competitive they were.

    Peptide
    Oxytocin
    Outcome
    Not applicableDependence of the oxytocin effect on cooperativeness or competitiveness
    Study

    n = 42

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Mental health and mood
    Studied dose
    Dose not stated

    Source sentences

    Summary
    This effect depended on the personality traits of cooperativeness or competitiveness.
    2 context sentences
    Summary · context
    Cooperation was assessed using a novel computerized drawing task that may be performed individually or cooperatively by two participants who coordinate their actions.
    Summary · context
    Using a within-subject crossover design, 42 participants performed the task alone and with a partner following the administration of placebo and oxytocin 1 week apart.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Registered trials1

Trials this study reports on, or that list this study as a reference. Registry data from ClinicalTrials.gov.

1 trial · 1 ongoing · source ClinicalTrials.gov (opens in a new tab)

RecruitingPhase 2NCT06364228

Intranasal Oxytocin Intervention for Caregivers to Persons With Dementia

University of Nebraskan = 32est. 20 Jun 2026 to est. Jun 2027

Stress

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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