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Study · Randomized controlled trial · n = 20 · 2013

5 results

Enhanced orienting of attention in response to emotional gaze cues after oxytocin administration in healthy young men.

Tollenaar MS, Chatzimanoli M, van der Wee NJ, Putman P

Psychoneuroendocrinology4 Apr 2013Cited by 57 (Europe PMC)

PMID23562249 (opens in a new tab)DOI10.1016/j.psyneuen.2013.02.018 (opens in a new tab)PepBankPUB-23562249
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

5 results from studies that gave the peptide. 5 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In healthy young men, oxytocin did not affect stress levels during the study compared with placebo.

    In plain wordsIn healthy young men, oxytocin did not change stress levels compared with placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changeStress levels
    Study

    n = 20

    Comparator
    Placebo
    Outcome group
    Anxiety and mood · Mental health and mood
    Studied dose
    24 IUAs given in this study (human).

    Source sentences

    Summary
    Oxytocin did not affect stress levels during the study, but significantly increased gaze cueing scores for happy and fearful expressions compared to placebo.
    1 context sentence
    Summary · context
    In a randomized placebo-controlled double-blind crossover study 20 healthy males received 24 IU of oxytocin or placebo.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In healthy young men, oxytocin significantly increased gaze cueing scores for happy expressions compared with placebo.

    In plain wordsIn healthy young men, oxytocin increased attention shifts toward the gaze of happy faces compared with placebo.

    Peptide
    Oxytocin
    Outcome
    IncreaseGaze cueing score for happy faces
    Study

    n = 20

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    24 IUAs given in this study (human).

    Source sentences

    Summary
    significantly increased gaze cueing scores for happy and fearful expressions compared to placebo.
    1 context sentence
    Summary · context
    In a randomized placebo-controlled double-blind crossover study 20 healthy males received 24 IU of oxytocin or placebo.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In healthy young men, oxytocin significantly increased gaze cueing scores for fearful expressions compared with placebo.

    In plain wordsIn healthy young men, oxytocin increased attention shifts toward the gaze of fearful faces compared with placebo.

    Peptide
    Oxytocin
    Outcome
    IncreaseGaze cueing score for fearful faces
    Study

    n = 20

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    24 IUAs given in this study (human).

    Source sentences

    Summary
    significantly increased gaze cueing scores for happy and fearful expressions compared to placebo.
    1 context sentence
    Summary · context
    In a randomized placebo-controlled double-blind crossover study 20 healthy males received 24 IU of oxytocin or placebo.
  4. 04HumanRandomized controlled trialEfficacy outcome

    In healthy young men, oxytocin had no effect on gaze cueing for neutral expressions.

    In plain wordsIn healthy young men, oxytocin did not change attention shifts toward the gaze of neutral faces.

    Peptide
    Oxytocin
    Outcome
    No significant changeGaze cueing score for neutral faces
    Study

    n = 20

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    24 IUAs given in this study (human).

    Source sentences

    Summary
    No effects were found for neutral expressions.
    1 context sentence
    Summary · context
    In a randomized placebo-controlled double-blind crossover study 20 healthy males received 24 IU of oxytocin or placebo.
  5. 05HumanRandomized controlled trialOther

    Trait anxiety or depression did not moderate the effect of oxytocin on gaze cueing.

    In plain wordsIn healthy young men, anxiety or depression traits did not change how oxytocin affected gaze cueing.

    Peptide
    Oxytocin
    Outcome
    No significant changeModeration of the gaze cueing effect by trait anxiety or depression
    Study

    n = 20

    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    24 IUAs given in this study (human).

    Source sentences

    Summary
    Trait anxiety or depression did not moderate the effect.
    1 context sentence
    Summary · context
    In a randomized placebo-controlled double-blind crossover study 20 healthy males received 24 IU of oxytocin or placebo.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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