In adults with Asperger syndrome, a single intranasal dose of oxytocin increased right amygdala activity to facial stimuli in a placebo-controlled crossover design.
In plain wordsIn adults with Asperger syndrome, one dose of oxytocin raised right amygdala brain activity to faces, compared with placebo.
- Peptide
- Oxytocin
- Outcome
- IncreaseRight amygdala activity to facial stimuli in adults with Asperger syndrome
- Study
n = 14
- Comparator
- Placebo
- Outcome group
- Cognition and memory · Nervous system and cognition
- Studied dose
- 24 IU single dose · intranasalAs given in this study (human).
Source sentences
After oxytocin treatment, right amygdala activity to facial stimuli increased in the AS group.
2 context sentences(design, population, supporting numbers)
A group of 14 individuals with AS and a group of 14 neurotypical control participants performed a face-matching and a house-matching task during functional magnetic resonance imaging.
The effects of a single dose of 24 IU intranasally administered oxytocin were tested in a randomized, placebo-controlled, within-subject, cross-over design.