In cultured thymic cells, AB-O induced T-cell precursor differentiation into CD4-positive helpers, with a weaker effect than R-1.
In plain wordsIn cells, Vilon induced helper T-cell differentiation less strongly than its analogue R-1.
- Peptide
- Vilon (KE)
- Outcome
- IncreaseT-cell precursor differentiation to CD4-positive helpers
- Study
human and ratn: not reported in source
Cultured thymic cells- Comparator
- R-1
- Outcome group
- Immune response · Immune and inflammation
- Studied dose
- Dose not stated
Source sentences
Dipeptide AB-O induced T-cells precursor differentiation towards CD4(+)T-helpers and its effect was weaker than that of dipeptide R-1.
2 context sentences(design, population, supporting numbers)
We studied molecular mechanisms of immunoprotective effects of two dipeptides, AB-O and R-1, on cultured human and rat thymic cells.
Immunomodulating effects of Vilon and its analogue in the culture of human and animal thymus cells.