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Study · In vitro (cells) · 2013

7 results

Effects of pancragen on the differentiation of pancreatic cells during their ageing.

Khavinson VKh, Durnova AO, Polyakova VO, Tolibova GH, Linkova NS, Kvetnoy IM, Kvetnaia TV, Tarnovskaya SI

Bulletin of experimental biology and medicine1 Feb 2013Cited by 7 (Europe PMC)

PMID23486591 (opens in a new tab)DOI10.1007/s10517-013-1987-6 (opens in a new tab)PepBankPUB-23486591
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study7

7 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Mechanism

    In young and aged pancreatic cultures, Pancragen stimulated acinar-cell Pdx1 expression.

    In plain wordsIn cells from young and aged pancreatic cultures, Pancragen increased acinar-cell Pdx1 expression.

    Peptide
    Pancragen (KEDW)
    Outcome
    IncreaseAcinar Pdx1 expression
    Study

    n: not reported in source

    young and aged pancreatic cell cultures
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Tetrapeptide pancragen stimulates the expression of differentiation factors of acinar (Pdx1, Ptfla) and islet of Langerhans (Pdx1, Pax6, Pax4, Foxa2, NKx2.2) cells in "young" and " aged" cultures.
  2. 02LabIn vitro (cells)Mechanism

    In young and aged pancreatic cultures, Pancragen stimulated acinar-cell Ptfla expression.

    In plain wordsIn cells from young and aged pancreatic cultures, Pancragen increased acinar-cell Ptfla expression.

    Peptide
    Pancragen (KEDW)
    Outcome
    IncreaseAcinar Ptfla expression
    Study

    n: not reported in source

    young and aged pancreatic cell cultures
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Tetrapeptide pancragen stimulates the expression of differentiation factors of acinar (Pdx1, Ptfla) and islet of Langerhans (Pdx1, Pax6, Pax4, Foxa2, NKx2.2) cells in "young" and " aged" cultures.
  3. 03LabIn vitro (cells)Mechanism

    In young and aged pancreatic cultures, Pancragen stimulated islet-cell Pdx1 expression.

    In plain wordsIn cells from young and aged pancreatic cultures, Pancragen increased islet-cell Pdx1 expression.

    Peptide
    Pancragen (KEDW)
    Outcome
    IncreaseIslet Pdx1 expression
    Study

    n: not reported in source

    young and aged pancreatic cell cultures
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Tetrapeptide pancragen stimulates the expression of differentiation factors of acinar (Pdx1, Ptfla) and islet of Langerhans (Pdx1, Pax6, Pax4, Foxa2, NKx2.2) cells in "young" and " aged" cultures.
  4. 04LabIn vitro (cells)Mechanism

    In young and aged pancreatic cultures, Pancragen stimulated islet-cell Pax6 expression.

    In plain wordsIn cells from young and aged pancreatic cultures, Pancragen increased islet-cell Pax6 expression.

    Peptide
    Pancragen (KEDW)
    Outcome
    IncreaseIslet Pax6 expression
    Study

    n: not reported in source

    young and aged pancreatic cell cultures
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Tetrapeptide pancragen stimulates the expression of differentiation factors of acinar (Pdx1, Ptfla) and islet of Langerhans (Pdx1, Pax6, Pax4, Foxa2, NKx2.2) cells in "young" and " aged" cultures.
  5. 05LabIn vitro (cells)Mechanism

    In young and aged pancreatic cultures, Pancragen stimulated islet-cell Pax4 expression.

    In plain wordsIn cells from young and aged pancreatic cultures, Pancragen increased islet-cell Pax4 expression.

    Peptide
    Pancragen (KEDW)
    Outcome
    IncreaseIslet Pax4 expression
    Study

    n: not reported in source

    young and aged pancreatic cell cultures
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Tetrapeptide pancragen stimulates the expression of differentiation factors of acinar (Pdx1, Ptfla) and islet of Langerhans (Pdx1, Pax6, Pax4, Foxa2, NKx2.2) cells in "young" and " aged" cultures.
  6. 06LabIn vitro (cells)Mechanism

    In young and aged pancreatic cultures, Pancragen stimulated islet-cell Foxa2 expression.

    In plain wordsIn cells from young and aged pancreatic cultures, Pancragen increased islet-cell Foxa2 expression.

    Peptide
    Pancragen (KEDW)
    Outcome
    IncreaseIslet Foxa2 expression
    Study

    n: not reported in source

    young and aged pancreatic cell cultures
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Tetrapeptide pancragen stimulates the expression of differentiation factors of acinar (Pdx1, Ptfla) and islet of Langerhans (Pdx1, Pax6, Pax4, Foxa2, NKx2.2) cells in "young" and " aged" cultures.
  7. 07LabIn vitro (cells)Mechanism

    In young and aged pancreatic cultures, Pancragen stimulated islet-cell NKx2.2 expression.

    In plain wordsIn cells from young and aged pancreatic cultures, Pancragen increased islet-cell NKx2.2 expression.

    Peptide
    Pancragen (KEDW)
    Outcome
    IncreaseIslet NKx2.2 expression
    Study

    n: not reported in source

    young and aged pancreatic cell cultures
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Tetrapeptide pancragen stimulates the expression of differentiation factors of acinar (Pdx1, Ptfla) and islet of Langerhans (Pdx1, Pax6, Pax4, Foxa2, NKx2.2) cells in "young" and " aged" cultures.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 17:05 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 16:35 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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