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Study · Randomized controlled trial · n = 81 · 2013

4 results

Improving social perception in schizophrenia: the role of oxytocin.

Fischer-Shofty M, Brüne M, Ebert A, Shefet D, Levkovitz Y, Shamay-Tsoory SG

Schizophrenia research19 Feb 2013Cited by 62 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. 4 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In patients with schizophrenia and healthy controls, participants were more accurate in judging intimacy and kinship after oxytocin than after placebo.

    In plain wordsIn patients with schizophrenia and healthy people, one dose of oxytocin made them more accurate at judging intimacy and kinship than placebo.

    Peptide
    Oxytocin
    Outcome
    IncreaseAccuracy of judging intimacy and kinship (all participants)
    Study

    n = 81

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Mental health and mood
    Studied dose
    24 IU · intranasal · single doseAs given in this study (human).

    Source sentences

    Summary
    Overall, the participants were more accurate in judging intimacy and kinship following the administration of oxytocin, as opposed to a placebo.
    2 context sentences
    Summary · context
    Thirty-five patients diagnosed with schizophrenia were compared with 46 psychologically healthy matched controls on their recognition of kinship and intimacy, using the Interpersonal Perception Task.
    Summary · context
    All participants received a single intranasal dose of 24 IU oxytocin or placebo, one week apart.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In patients with schizophrenia and healthy controls, oxytocin produced no significant improvement in recognition of intimacy in either group.

    In plain wordsIn patients with schizophrenia and healthy people, one dose of oxytocin did not improve recognition of intimacy in either group.

    Peptide
    Oxytocin
    Outcome
    No significant changeRecognition of intimacy in patients and controls
    Study

    n = 81

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Mental health and mood
    Studied dose
    24 IU · intranasal · single doseAs given in this study (human).

    Source sentences

    Summary
    or in the recognition of intimacy in either group.
    2 context sentences
    Summary · context
    Thirty-five patients diagnosed with schizophrenia were compared with 46 psychologically healthy matched controls on their recognition of kinship and intimacy, using the Interpersonal Perception Task.
    Summary · context
    All participants received a single intranasal dose of 24 IU oxytocin or placebo, one week apart.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In healthy controls, oxytocin produced no significant improvement in recognition of kinship.

    In plain wordsIn healthy people, one dose of oxytocin did not improve recognition of kinship.

    Peptide
    Oxytocin
    Outcome
    No significant changeRecognition of kinship in healthy controls
    Study

    n = 46

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Mental health and mood
    Studied dose
    24 IU · intranasal · single doseAs given in this study (human).

    Source sentences

    Summary
    no such effect was observed in the control group or in the recognition of intimacy in either group.
    2 context sentences
    Summary · context
    Thirty-five patients diagnosed with schizophrenia were compared with 46 psychologically healthy matched controls on their recognition of kinship and intimacy, using the Interpersonal Perception Task.
    Summary · context
    All participants received a single intranasal dose of 24 IU oxytocin or placebo, one week apart.
  4. 04HumanRandomized controlled trialEfficacy outcome

    In patients with schizophrenia, oxytocin significantly improved recognition of kinship compared with placebo.

    In plain wordsIn patients with schizophrenia, one dose of oxytocin improved recognition of kinship compared with placebo.

    Peptide
    Oxytocin
    Outcome
    IncreaseRecognition of kinship in patients with schizophrenia
    Study

    n = 35

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Mental health and mood
    Studied dose
    24 IU · intranasal · single doseAs given in this study (human).

    Source sentences

    Summary
    only the recognition of kinship improved significantly in the patient group, whereas no such effect was observed in the control group or in the recognition of intimacy in either group.
    2 context sentences
    Summary · context
    Thirty-five patients diagnosed with schizophrenia were compared with 46 psychologically healthy matched controls on their recognition of kinship and intimacy, using the Interpersonal Perception Task.
    Summary · context
    All participants received a single intranasal dose of 24 IU oxytocin or placebo, one week apart.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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