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Study · In vitro (cells) · 2013

1 result

Collagen stimulating effect of peptide amphiphile C16-KTTKS on human fibroblasts.

Jones RR, Castelletto V, Connon CJ, Hamley IW

Molecular pharmaceutics4 Feb 2013Cited by 59 (Europe PMC)

Summary

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Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Activity measurement

    In human dermal and corneal fibroblasts, C16-KTTKS stimulated collagen production in a concentration-dependent manner near its critical aggregation concentration.

    In plain wordsIn cells, C16-KTTKS increased collagen production as its concentration increased near the point where it forms aggregates.

    Outcome
    IncreaseCollagen production
    Study

    humann: not reported in source

    Human dermal and corneal fibroblasts
    Outcome group
    Skin and hair · Skin and wound
    Studied dose
    Dose not stated

    Source sentences

    Summary
    We prove that C16-KTTKS stimulates collagen production in a concentration-dependent manner close to the critical aggregation concentration determined from pyrene fluorescence spectroscopy.
    1 context sentence
    Summary · context
    The collagen production of human dermal and corneal fibroblasts in contact with solutions of the peptide amphiphile (PA) C16-KTTKS is investigated and related to its self-assembly into nanotape structures.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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