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Study · Measured the body's own peptide · 2013

3 results

Reduced plasma oxytocin levels in female patients with borderline personality disorder.

Bertsch K, Schmidinger I, Neumann ID, Herpertz SC

Hormones and behavior29 Nov 2012Cited by 111 (Europe PMC)

PMID23201337 (opens in a new tab)DOI10.1016/j.yhbeh.2012.11.013 (opens in a new tab)PepBankPUB-23201337
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In women with borderline personality disorder, plasma oxytocin concentrations were lower than in women without it, also after controlling for estrogen, progesterone and contraceptive intake.

    In plain wordsIn women with borderline personality disorder, the body's own oxytocin levels in blood were lower than in women without it.

    Peptide
    Oxytocin
    Outcome
    DecreasePlasma oxytocin in women with borderline personality disorder
    Study

    n: not reported in source

    Comparator
    Women without BPD
    Outcome group
    Endogenous peptide levels · Mental health and mood

    Source sentences

    Summary
    Women diagnosed with BPD had significantly reduced oxytocin concentrations, even after controlling for estrogen, progesterone, and contraceptive intake.
    1 context sentence
    Summary · context
    In the present study, we compared plasma oxytocin levels of women with and without BPD in the follicular phase and assessed the relationship between oxytocin concentrations and childhood traumata.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    In women, plasma oxytocin correlated negatively with experiences of childhood trauma, in particular emotional neglect and abuse.

    In plain wordsIn women, lower natural oxytocin levels in blood were linked to more childhood trauma, especially emotional neglect and abuse.

    Peptide
    Oxytocin
    Outcome
    DecreasePlasma oxytocin and childhood trauma
    Study

    n: not reported in source

    Outcome group
    Endogenous peptide levels · Mental health and mood

    Source sentences

    Summary
    In addition, plasma oxytocin correlated negatively with experiences of childhood traumata, in particular with emotional neglect and abuse.
    1 context sentence
    Summary · context
    In the present study, we compared plasma oxytocin levels of women with and without BPD in the follicular phase and assessed the relationship between oxytocin concentrations and childhood traumata.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelObservational studyOther

    Mediation analyses did not support plasma oxytocin as a prominent mediator in the link between childhood trauma and borderline personality disorder.

    In plain wordsNatural oxytocin levels did not appear to explain the link between childhood trauma and borderline personality disorder.

    Peptide
    Oxytocin
    Outcome
    No significant changeOxytocin as mediator between childhood trauma and BPD
    Study

    n: not reported in source

    Outcome group
    Endogenous peptide levels · Mental health and mood

    Source sentences

    Summary
    The results of mediation analyses do not support a model of oxytocin being a prominent mediator in the link between childhood trauma and BPD.
    1 context sentence
    Summary · context
    In the present study, we compared plasma oxytocin levels of women with and without BPD in the follicular phase and assessed the relationship between oxytocin concentrations and childhood traumata.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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