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Study · Measured the body's own peptide · 2012

1 result

β-hydroxy-β-methylbutyrate did not enhance high intensity resistance training-induced improvements in myofiber dimensions and myogenic capacity in aged female rats.

Kim JS, Park YM, Lee SR, Masad IS, Khamoui AV, Jo E, Park BS, Arjmandi BH, Panton LB, Lee WJ, Grant SC

Molecules and cells6 Nov 2012Cited by 17 (Europe PMC)

PMID23149873 (opens in a new tab)PMCIDPMC3887788 (opens in a new tab)DOI10.1007/s10059-012-0196-x (opens in a new tab)PepBankPUB-23149873
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In aged female rats, resistance training increased the body's own MGF mRNA in muscle in both the HMB and non-HMB groups.

    In plain wordsIn aged female rats, resistance training raised the body's own MGF in muscle, with or without HMB.

    Peptide
    MGF / PEG-MGF
    Outcome
    IncreaseMGF mRNA expression in muscle after resistance training
    Study

    ratn = 12

    Aged female Sprague-Dawley rats
    Outcome group
    Muscle injury and repair · Musculoskeletal

    Measurements

    MGF mRNA change
    32 to 40%
    HMB and non-HMB groups

    Source sentences

    Summary
    MGF and myogenin increased significantly in both groups (+32-40%).
    1 context sentence
    Summary · context
    Nineteen-month old female Sprague-Dawley rats were randomly divided into three groups: HMB (0.48 g/kg/d; n = 6), non-HMB (n = 6), and control (n = 4).

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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