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Study · Animal study (in vivo) · rat · 2012

2 results

Antistress effect of Semax in the course of recovery of spleen lymphoid structures after the stress in rats with different behavioral activity.

Bakhmet AA, Koplik EV

Bulletin of experimental biology and medicine1 Sept 2012Cited by 3 (Europe PMC)

PMID23113251 (opens in a new tab)DOI10.1007/s10517-012-1792-7 (opens in a new tab)PepBankPUB-23113251
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In Wistar rats, preliminary administration of Semax alleviated stress-induced proliferation of macrophages in the spleen on days 1, 3 and 14 after stress.

    In plain wordsIn rats, Semax given before stress reduced the stress-related growth of macrophages in the spleen.

    Peptide
    Semax
    Outcome
    DecreaseStress-induced macrophage proliferation in spleen
    Study

    ratn: not reported in source

    Wistar rats after 1-h stress, spleen lymphoid structures
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Preliminary administration of Semax alleviates stress-induced proliferation of macrophages and destructive processes in functionally active zones of the rat spleen on days 1, 3, and 14 after the stress exposure
    1 context sentence
    Summary · context
    We studied the effect of antistress peptide Semax, an ACTH4-10 analogue, on the cellular composition of spleen lymphoid structures in Wistar rats with different stress tolerance in the course of post-stress recovery (days 1, 3, 14, and 30).
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In Wistar rats, preliminary administration of Semax alleviated stress-induced destructive processes in functionally active zones of the spleen on days 1, 3 and 14 after stress.

    In plain wordsIn rats, Semax given before stress reduced stress-related tissue damage in active zones of the spleen.

    Peptide
    Semax
    Outcome
    DecreaseStress-induced destructive processes in spleen
    Study

    ratn: not reported in source

    Wistar rats after 1-h stress, spleen lymphoid structures
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Preliminary administration of Semax alleviates stress-induced proliferation of macrophages and destructive processes in functionally active zones of the rat spleen on days 1, 3, and 14 after the stress exposure
    1 context sentence
    Summary · context
    We studied the effect of antistress peptide Semax, an ACTH4-10 analogue, on the cellular composition of spleen lymphoid structures in Wistar rats with different stress tolerance in the course of post-stress recovery (days 1, 3, 14, and 30).

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 19:08 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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