In Wistar rats, microionophoretic application of DSIP reduced the sensitivity of dorsal hippocampal neurons to lateral hypothalamus stimulation; only 28% of neurons responded.
In plain wordsIn rats, DSIP made nerve cells in the hippocampus respond less to stimulation of a nearby brain area.
- Outcome
- DecreaseShare of hippocampal neurons responding to lateral hypothalamus stimulation
- Study
ratn: not reported in source
Wistar rats, dorsal hippocampus neurons, lateral hypothalamus stimulation- Outcome group
- Brain and neuronal activity · Nervous system and cognition
- Studied dose
- Dose not stated · microionophoretic applicationAs given in this study (rat).
Measurements
- neurons responding to stimulation
- 28%
- after DSIP application
Source sentences
After application of delta-sleep-inducing peptide, only 28% neurons responded to stimulation.
2 context sentences(design, population, supporting numbers)
Thus, delta-sleep-inducing peptide reduced the sensitivity of hippocampal neurons to stimulation of the lateral hypothalamus.
In Wistar rats preliminary tested in an open field, the reactions of 57 neurons of the dorsal hippocampus were analyzed during lateral hypothalamus stimulation and microionophoretic application of delta-sleep-inducing peptide.