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Study · Animal study (in vivo) · rat · 2012

2 results

[The comparison of neuroprotective action of antibodies to glutamate and drug preparation semax in the focal ischemic damage of the brain prefrontal cortex of rats].

Romanova GA, Shakova FM, Davydova TV

Patologicheskaia fiziologiia i eksperimental'naia terapiia1 Jul 2012

PMID23072114 (opens in a new tab)PepBankPUB-23072114
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats with photochemically induced thrombosis of the prefrontal cortex, intranasal semax at 250 mkg/kg daily for six postoperative days decreased cortex damage volume.

    In plain wordsIn rats with induced brain damage, nasal semax reduced the size of the damaged cortex area.

    Peptide
    Semax
    Outcome
    DecreaseCortex damage volume
    Study

    ratn: not reported in source

    Bilateral photochemically induced thrombosis of the prefrontal cortex
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    250 mkg/kg/daily · intranasal · six postoperative daysAs given in this study (rat).

    Source sentences

    Summary
    Intranasal injection semax (250 mkg/kg/daily during six postoperative days) and AB-Glu (250 mkg/kg in 1 hour after phototrombosis) demonstrate diminishing of cortex damage volume and relieve preservation and reproduction rat passive avoidance reflex, acquired before bilateral photochemically induced…
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats with photochemically induced thrombosis of the prefrontal cortex, intranasal semax at 250 mkg/kg daily for six postoperative days preserved the passive avoidance reflex acquired before the injury.

    In plain wordsIn rats with induced brain damage, nasal semax helped keep a learned avoidance response that rats acquired before the damage.

    Peptide
    Semax
    Outcome
    IncreasePreservation and reproduction of passive avoidance reflex
    Study

    ratn: not reported in source

    Bilateral photochemically induced thrombosis of the prefrontal cortex
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    250 mkg/kg/daily · intranasal · six postoperative daysAs given in this study (rat).

    Source sentences

    Summary
    Intranasal injection semax (250 mkg/kg/daily during six postoperative days) and AB-Glu (250 mkg/kg in 1 hour after phototrombosis) demonstrate diminishing of cortex damage volume and relieve preservation and reproduction rat passive avoidance reflex, acquired before bilateral photochemically induced…

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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