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Study · Randomized controlled trial · n = 104 · 2012

4 results

Effects of oxytocin on human social approach measured using intimacy equilibriums.

Liu JC, Guastella AJ, Dadds MR

Hormones and behavior19 Sept 2012Cited by 16 (Europe PMC)

PMID22999976 (opens in a new tab)DOI10.1016/j.yhbeh.2012.09.002 (opens in a new tab)PepBankPUB-22999976
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. 4 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In paired undergraduate strangers, oxytocin did not facilitate social approach by increasing the intimacy equilibrium.

    In plain wordsIn paired undergraduates meeting a stranger, oxytocin did not increase the overall balance of closeness compared with placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changeIntimacy equilibrium between two strangers
    Study

    n = 104

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Based on this notion, our results suggest that oxytocin does not facilitate social approach by increasing the intimacy equilibrium between two strangers.
    2 context sentences
    Summary · context
    We tested this by introducing undergraduate students to opposite-gendered strangers, with each member of the pair having taken either oxytocin or placebo.
    Summary · context
    One hundred and four undergraduate students were paired up and engaged in a face-to-face conversation structured with a series of intimate topics for discussion.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In undergraduate women talking with strangers, oxytocin increased conversational intimacy compared with placebo.

    In plain wordsIn female undergraduates talking with a stranger, oxytocin made conversation more intimate than placebo did.

    Peptide
    Oxytocin
    Outcome
    IncreaseConversational intimacy in female participants
    Study

    n: not reported in source

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    oxytocin increased conversational intimacy in female but not male participants
    2 context sentences
    Summary · context
    We tested this by introducing undergraduate students to opposite-gendered strangers, with each member of the pair having taken either oxytocin or placebo.
    Summary · context
    One hundred and four undergraduate students were paired up and engaged in a face-to-face conversation structured with a series of intimate topics for discussion.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In undergraduate men talking with strangers, oxytocin did not increase conversational intimacy compared with placebo.

    In plain wordsIn male undergraduates talking with a stranger, oxytocin did not make conversation more intimate than placebo did.

    Peptide
    Oxytocin
    Outcome
    No significant changeConversational intimacy in male participants
    Study

    n: not reported in source

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    oxytocin increased conversational intimacy in female but not male participants
    2 context sentences
    Summary · context
    We tested this by introducing undergraduate students to opposite-gendered strangers, with each member of the pair having taken either oxytocin or placebo.
    Summary · context
    One hundred and four undergraduate students were paired up and engaged in a face-to-face conversation structured with a series of intimate topics for discussion.
  4. 04HumanRandomized controlled trialEfficacy outcome

    In undergraduates talking with strangers, oxytocin was matched with compensatory decreases in eye-contact relative to placebo.

    In plain wordsIn undergraduates talking with a stranger, oxytocin went with less eye contact than placebo.

    Peptide
    Oxytocin
    Outcome
    DecreaseEye-contact
    Study

    n: not reported in source

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    but that this was matched with compensatory decreases in eye-contact (relative to placebo).
    2 context sentences
    Summary · context
    We tested this by introducing undergraduate students to opposite-gendered strangers, with each member of the pair having taken either oxytocin or placebo.
    Summary · context
    One hundred and four undergraduate students were paired up and engaged in a face-to-face conversation structured with a series of intimate topics for discussion.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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