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Study · In vitro (cells) · 2012

2 results

Cerebrolysin administration reduces oxidative stress-induced apoptosis in lymphocytes from healthy individuals.

Formichi P, Radi E, Battisti C, Di Maio G, Muresanu D, Federico A

Journal of cellular and molecular medicine1 Nov 2012Cited by 16 (Europe PMC)

PMID22882711 (opens in a new tab)PMCIDPMC4118252 (opens in a new tab)DOI10.1111/j.1582-4934.2012.01615.x (opens in a new tab)PepBankPUB-22882711
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Efficacy outcome

    In human peripheral blood lymphocytes, Cerebrolysin significantly reduced apoptosis after dRib treatment.

    In plain wordsIn cells, Cerebrolysin reduced apoptosis after dRib treatment compared with cells without Cerebrolysin.

    Peptide
    Cerebrolysin
    Outcome
    DecreaseInduced apoptosis
    Study

    humann = 10

    Peripheral blood lymphocytes
    Comparator
    dRib treatment without Cerebrolysin
    Outcome group
    Cell viability and death · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Our results showed that Cerebrolysin significantly reduced the number of apoptotic PBLs after dRib treatment, although it had no significative effects on cells cultured in standard conditions.
    1 context sentence
    Summary · context
    Peripheral blood lymphocytes (PBLs) from 10 individuals were used as cell model; 2-deoxy-D-ribose (dRib), a highly reducing sugar, was used as paradigm pro-apoptotic stimulus.
  2. 02LabIn vitro (cells)Efficacy outcome

    In human lymphocytes cultured under standard conditions, Cerebrolysin had no significant effect on apoptosis.

    In plain wordsIn cells under standard conditions, Cerebrolysin did not significantly change apoptosis compared with cells without Cerebrolysin.

    Peptide
    Cerebrolysin
    Outcome
    No significant changeSpontaneous apoptosis
    Study

    humann = 10

    Peripheral blood lymphocytes
    Comparator
    Standard culture without Cerebrolysin
    Outcome group
    Cell viability and death · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Our results showed that Cerebrolysin significantly reduced the number of apoptotic PBLs after dRib treatment, although it had no significative effects on cells cultured in standard conditions.
    1 context sentence
    Summary · context
    Peripheral blood lymphocytes (PBLs) from 10 individuals were used as cell model; 2-deoxy-D-ribose (dRib), a highly reducing sugar, was used as paradigm pro-apoptotic stimulus.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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