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Study · Animal study (in vivo) · rat · 2012

2 results

[Effect of selank on the main carboxypeptidases in the rat nervous tissue].

Solov'ev VB, Gengin MT, Sollertinskaia TN, Latynova IV, Zhivaeva LV

Zhurnal evoliutsionnoi biokhimii i fiziologii1 May 2012Cited by 1 (Europe PMC)

PMID22827026 (opens in a new tab)DOI10.1134/s0022093012030073 (opens in a new tab)PepBankPUB-22827026
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In rat nervous tissue, a single dose of selank changed carboxypeptidase H activity for 24 hours.

    In plain wordsIn rat nervous tissue, one dose of selank changed the activity of the enzyme carboxypeptidase H for 24 hours.

    Peptide
    Selank
    Outcome
    Direction not reportedCarboxypeptidase H activity after single dose
    Study

    ratn: not reported in source

    Nervous tissue
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The preparation has been shown to cause long, preserved for 24 h changes of activities of these carboxypeptidases.
    1 context sentence
    Summary · context
    Effect of single selank administration on activity of carboxypeptidase H and of phenylmethylsulfonylfluoride-inhibited carboxypeptidase - enzymes detaching arginine and lysine from C-terminus of molecules-precursors of biologically active peptides was studied.
  2. 02AnimalAnimal study (in vivo)Mechanism

    In rat nervous tissue, a single dose of selank changed the activity of phenylmethylsulfonylfluoride-inhibited carboxypeptidase for 24 hours.

    In plain wordsIn rat nervous tissue, one dose of selank changed the activity of a second carboxypeptidase enzyme for 24 hours.

    Peptide
    Selank
    Outcome
    Direction not reportedPMSF-inhibited carboxypeptidase activity after single dose
    Study

    ratn: not reported in source

    Nervous tissue
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The preparation has been shown to cause long, preserved for 24 h changes of activities of these carboxypeptidases.
    1 context sentence
    Summary · context
    Effect of single selank administration on activity of carboxypeptidase H and of phenylmethylsulfonylfluoride-inhibited carboxypeptidase - enzymes detaching arginine and lysine from C-terminus of molecules-precursors of biologically active peptides was studied.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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