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Study · Animal study (in vivo) · rat · 2012

2 results

Semax attenuates the influence of neonatal maternal deprivation on the behavior of adolescent white rats.

Volodina MA, Sebentsova EA, Glazova NY, Levitskaya NG, Andreeva LA, Manchenko DM, Kamensky AA, Myasoedov NF

Bulletin of experimental biology and medicine1 Mar 2012Cited by 2 (Europe PMC)

PMID22803132 (opens in a new tab)DOI10.1007/s10517-012-1574-2 (opens in a new tab)PepBankPUB-22803132
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats with neonatal maternal deprivation, intranasal Semax weakened the impact of deprivation on body weight, which deprivation had slowed.

    In plain wordsIn young rats raised with maternal deprivation, Semax reduced the effect of deprivation on body weight.

    Peptide
    Semax
    Outcome
    IncreaseBody weight after maternal deprivation
    Study

    ratn: not reported in source

    Neonatal maternal deprivation (5 h/day, postnatal days 1 to 14), adolescent white rats
    Outcome group
    Body weight · Metabolic and weight
    Studied dose
    0.05 mg/kg · intranasal · postnatal days 15 to 28As given in this study (rat).

    Source sentences

    Summary
    Semax weakened the impact of deprivation on animal body weight
    2 context sentences
    Summary · context
    It was found that maternal deprivation decelerated the growth of young rats
    Summary · context
    Here we studied the possibility of reducing the negative consequences of deprivation by daily intranasal treatment with Semax, an analog of ACTH(4-10), in a dose of 0.05 mg/kg from postnatal days 15 to 28.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats with neonatal maternal deprivation, intranasal Semax normalized the levels of anxiety.

    In plain wordsIn young rats raised with maternal deprivation, Semax brought anxiety levels back to normal.

    Peptide
    Semax
    Outcome
    DecreaseAnxiety after maternal deprivation
    Study

    ratn: not reported in source

    Neonatal maternal deprivation (5 h/day, postnatal days 1 to 14), adolescent white rats
    Outcome group
    Anxiety and mood · Mental health and mood
    Studied dose
    0.05 mg/kg · intranasal · postnatal days 15 to 28As given in this study (rat).

    Source sentences

    Summary
    normalized the levels of anxiety in rats.
    2 context sentences
    Summary · context
    increased anxiety in one-month-old animals.
    Summary · context
    Here we studied the possibility of reducing the negative consequences of deprivation by daily intranasal treatment with Semax, an analog of ACTH(4-10), in a dose of 0.05 mg/kg from postnatal days 15 to 28.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 19:08 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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