[Effect of delta-sleep inducing peptide on the functional activity of some organs and tissues of rats during physiological aging].

Bondarenko TI, Maĭboroda EA, Mikhaleva II, Prudchenko IA

Advances in gerontology = Uspekhi gerontologii1 Jan 2012

PMID22708458PepBankPUB-22708458

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

01AnimalAnimal study (in vivo)Efficacy outcome
In rats aged 2-24 months, subcutaneous DSIP had a hepatoprotective effect.
In plain wordsIn rats, DSIP injections protected the liver.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
Not applicableHepatoprotective effect
Study
ratn: not reported in source
physiological aging, rats aged 2-24 months
Outcome group
Liver fat and liver function · Liver
Studied dose
100 mg/kg animal body weight · subcutaneous · 5 consecutive days every monthAs given in this study (rat).
Source sentences
Summary
The authors show that exogenous delta-sleep inducing peptide (DSIP) injected subcutaneously to the rats in the age of 2-24 months of postnatal development in a dose of 100 mg/kg of animal body weight in courses for 5 consecutive days every month, has a hepatoprotective effect.
Report a problemFND-2270845801
02AnimalAnimal study (in vivo)Efficacy outcome
In rats aged 2-24 months, DSIP did not affect the functional activity of the pancreas.
In plain wordsIn rats, DSIP injections did not affect how the pancreas worked.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
No significant changePancreas functional activity
Study
ratn: not reported in source
physiological aging, rats aged 2-24 months
Outcome group
Glycemic control · Endocrine and hormones
Studied dose
100 mg/kg animal body weight · subcutaneous · 5 consecutive days every monthAs given in this study (rat).
Source sentences
Summary
DSIP does not affect the functional activity of the pancreas
1 context sentence(design, population, supporting numbers)
Summary · context
injected subcutaneously to the rats in the age of 2-24 months of postnatal development in a dose of 100 mg/kg of animal body weight in courses for 5 consecutive days every month
Report a problemFND-2270845802
03AnimalAnimal study (in vivo)Mechanism
In rats aged 2-24 months, DSIP was not involved in the regulation of calcium homeostasis.
In plain wordsIn rats, DSIP injections did not take part in the regulation of calcium balance.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
No significant changeCalcium homeostasis
Study
ratn: not reported in source
physiological aging, rats aged 2-24 months
Outcome group
Aging markers · Endocrine and hormones
Studied dose
100 mg/kg animal body weight · subcutaneous · 5 consecutive days every monthAs given in this study (rat).
Source sentences
Summary
and is not involved in the regulation of calcium homeostasis in the physiological aging of the organism.
1 context sentence(design, population, supporting numbers)
Summary · context
injected subcutaneously to the rats in the age of 2-24 months of postnatal development in a dose of 100 mg/kg of animal body weight in courses for 5 consecutive days every month
Report a problemFND-2270845803

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
12 Oct 2026, 17:28 UTC
Study results updated
Version 1
9 Oct 2026, 03:04 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

MeSH terms

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