In men with azoospermia, sperm retrieval was similar with pretreatment testosterone below 300 ng/dl after pooled medical therapy (52% versus 56%).
In plain wordsIn men with azoospermia, pooled testosterone optimization therapy yielded similar sperm retrieval to men with higher baseline testosterone.
- Outcome
- No significant changeSperm retrieval by baseline testosterone
- Study
n = 736
- Comparator
- Baseline testosterone greater than 300 ng/dl
- Outcome group
- Sex hormones and fertility · Reproductive and sexual health
Measurements
- Sperm retrieval rate
- 52%
- 348 men with pretreatment testosterone less than 300 ng/dl, pooled medical therapy
- Sperm retrieval rate
- 56%
- 388 men with baseline testosterone greater than 300 ng/dl
- p value for sperm retrieval by baseline testosterone
- 0.29 p value
- Pretreatment testosterone less than 300 versus baseline testosterone greater than 300 ng/dl
- Patient count in lower-testosterone group
- 348 men
- Pretreatment testosterone less than 300 ng/dl, sperm retrieval comparison
- Patient count in higher-testosterone group
- 388 men
- Baseline testosterone greater than 300 ng/dl, sperm retrieval comparison
Source sentences
In the remaining 348 men with pretreatment testosterone levels less than 300 ng/dl, the sperm retrieval rate was similar (52%, p = 0.29).
Of the 736 men who had preoperative hormonal data 388 (53%) had baseline testosterone levels greater than 300 ng/dl.
2 context sentences(design, population, supporting numbers)
The sperm retrieval rate in these men was 56%.
Patients with preoperative testosterone levels less than 300 ng/dl were treated with aromatase inhibitors, clomiphene citrate or human chorionic gonadotropin before microdissection testicular sperm extraction with the goal of optimizing testosterone levels.
In this study, hCG (human chorionic gonadotropin) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking hCG (human chorionic gonadotropin).