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Study · Measured the body's own peptide · 2013

3 results

Effects of couple interactions and relationship quality on plasma oxytocin and cardiovascular reactivity: empirical findings and methodological considerations.

Smith TW, Uchino BN, MacKenzie J, Hicks AM, Campo RA, Reblin M, Grewen KM, Amico JA, Light KC

International journal of psychophysiology : official journal of the International Organization of Psychophysiology26 Apr 2012Cited by 22 (Europe PMC)

PMID22543270 (opens in a new tab)PMCIDPMC5045263 (opens in a new tab)DOI10.1016/j.ijpsycho.2012.04.006 (opens in a new tab)PepBankPUB-22543270
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelNon-randomized trialOther

    In younger couples, better relationship quality had a small, marginally significant inverse association with the body's own plasma oxytocin levels.

    In plain wordsIn younger couples, better relationship quality was linked to slightly lower levels of the body's own oxytocin in blood.

    Peptide
    Oxytocin
    Outcome
    DecreaseRelationship quality and plasma oxytocin
    Study

    n = 180

    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    relationship quality had a small, marginally significant inverse association with plasma oxytocin levels, and neither positive nor negative couple interactions evoked change in plasma oxytocin.
    1 context sentence
    Summary · context
    In this study of 180 younger couples, relationship quality had a small, marginally significant inverse association with plasma oxytocin levels, and neither positive nor negative couple interactions evoked change in plasma oxytocin.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelNon-randomized trialOther

    In younger couples, positive couple interactions evoked no change in plasma oxytocin.

    In plain wordsIn younger couples, positive interactions did not change the body's own oxytocin levels in blood.

    Peptide
    Oxytocin
    Outcome
    No significant changePlasma oxytocin change after positive couple interactions
    Study

    n = 180

    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    neither positive nor negative couple interactions evoked change in plasma oxytocin.
    1 context sentence
    Summary · context
    In this study of 180 younger couples, relationship quality had a small, marginally significant inverse association with plasma oxytocin levels, and neither positive nor negative couple interactions evoked change in plasma oxytocin.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelNon-randomized trialOther

    In younger couples, negative couple interactions evoked no change in plasma oxytocin.

    In plain wordsIn younger couples, negative interactions did not change the body's own oxytocin levels in blood.

    Peptide
    Oxytocin
    Outcome
    No significant changePlasma oxytocin change after negative couple interactions
    Study

    n = 180

    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    neither positive nor negative couple interactions evoked change in plasma oxytocin.
    1 context sentence
    Summary · context
    In this study of 180 younger couples, relationship quality had a small, marginally significant inverse association with plasma oxytocin levels, and neither positive nor negative couple interactions evoked change in plasma oxytocin.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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