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Study · Case report or series · n = 1 · 2012

4 results

Dramatic improvement in sexual function induced by intranasal oxytocin.

MacDonald K, Feifel D

The journal of sexual medicine28 Mar 2012Cited by 32 (Europe PMC)

PMID22458365 (opens in a new tab)DOI10.1111/j.1743-6109.2012.02703.x (opens in a new tab)PepBankPUB-22458365
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. 4 results from people.

  1. 01HumanCase report or seriesEfficacy outcome

    In one man treated with intranasal oxytocin for social anxiety, oxytocin positively affected libido.

    In plain wordsIn one man, intranasal oxytocin was followed by better sex drive. This is a single case.

    Peptide
    Oxytocin
    Outcome
    IncreaseLibido
    Study

    n = 1

    Outcome group
    Sexual function · Reproductive and sexual health
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    Oxytocin positively impacted a number of components of sexual function, including libido, erection, and orgasm, and was well tolerated.
    2 context sentences
    Summary · context
    This is a case report on a male who had significant, broad-spectrum improvements in sexual function during a course of intranasal oxytocin treatment for social anxiety.
    Summary · context
    After obtaining informed consent, an off-label trial of intranasal oxytocin was administered targeting his social anxiety and relational avoidance.
  2. 02HumanCase report or seriesEfficacy outcome

    In one man treated with intranasal oxytocin for social anxiety, oxytocin positively affected erection.

    In plain wordsIn one man, intranasal oxytocin was followed by better erections. This is a single case.

    Peptide
    Oxytocin
    Outcome
    IncreaseErection
    Study

    n = 1

    Outcome group
    Sexual function · Reproductive and sexual health
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    Oxytocin positively impacted a number of components of sexual function, including libido, erection, and orgasm, and was well tolerated.
    2 context sentences
    Summary · context
    This is a case report on a male who had significant, broad-spectrum improvements in sexual function during a course of intranasal oxytocin treatment for social anxiety.
    Summary · context
    After obtaining informed consent, an off-label trial of intranasal oxytocin was administered targeting his social anxiety and relational avoidance.
  3. 03HumanCase report or seriesEfficacy outcome

    In one man treated with intranasal oxytocin for social anxiety, oxytocin positively affected orgasm.

    In plain wordsIn one man, intranasal oxytocin was followed by better orgasm. This is a single case.

    Peptide
    Oxytocin
    Outcome
    IncreaseOrgasm
    Study

    n = 1

    Outcome group
    Sexual function · Reproductive and sexual health
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    Oxytocin positively impacted a number of components of sexual function, including libido, erection, and orgasm, and was well tolerated.
    2 context sentences
    Summary · context
    This is a case report on a male who had significant, broad-spectrum improvements in sexual function during a course of intranasal oxytocin treatment for social anxiety.
    Summary · context
    After obtaining informed consent, an off-label trial of intranasal oxytocin was administered targeting his social anxiety and relational avoidance.
  4. 04HumanCase report or seriesSafety outcome

    In one man treated with intranasal oxytocin, the treatment was well tolerated.

    In plain wordsIn one man, intranasal oxytocin was well tolerated. This is a single case.

    Peptide
    Oxytocin
    Outcome
    Not applicableTolerability
    Study

    n = 1

    Outcome group
    Adverse events · Whole body
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    and was well tolerated.
    2 context sentences
    Summary · context
    This is a case report on a male who had significant, broad-spectrum improvements in sexual function during a course of intranasal oxytocin treatment for social anxiety.
    Summary · context
    After obtaining informed consent, an off-label trial of intranasal oxytocin was administered targeting his social anxiety and relational avoidance.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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