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Study · Not a test of the peptide alone · 2012

3 results

Characterization and identification of a C-terminal amidated mechano growth factor (MGF) analogue in black market products.

Esposito S, Esposito S, Deventer K, Van Eenoo P

Rapid communications in mass spectrometry : RCM1 Mar 2012Cited by 21 (Europe PMC)

PMID22328223 (opens in a new tab)DOI10.1002/rcm.6144 (opens in a new tab)PepBankPUB-22328223
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, MGF / PEG-MGF was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking MGF / PEG-MGF.

  1. 01LabNot a test of MGF / PEG-MGF aloneIn vitro (cell-free)Other

    In black market preparations, all y series ions from (y(1))(+) differed by 1 m/z unit in nominal mass from human MGF reference standard.

    In plain wordsIn lab tests, black market products showed a small mass difference from reference MGF.

    Peptide
    MGF / PEG-MGF
    Outcome
    Not applicabley series ion mass difference from reference MGF
    Study

    n: not reported in source

    Outcome group
    Receptor activity and mechanism · Pharmacology

    Source sentences

    Summary
    HCD scans of the analytes showed the presence of common b series product ions in the black market preparations and the human MGF reference standard, but all the y series ions starting from (y(1))(+) exhibited a difference of 1 m/z unit in nominal mass.

    In this study, MGF / PEG-MGF was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking MGF / PEG-MGF.

  2. 02LabNot a test of MGF / PEG-MGF aloneIn vitro (cell-free)Other

    High-resolution data showed that two black market products were both C-terminal amidated analogues of human MGF.

    In plain wordsIn lab tests, two black market products were found to be amidated versions of MGF.

    Peptide
    MGF / PEG-MGF
    Outcome
    Not applicableIdentification of C-terminal amidated MGF analogues
    Study

    n: not reported in source

    Outcome group
    Receptor activity and mechanism · Pharmacology

    Source sentences

    Summary
    High-resolution data demonstrated that the black market products were both C-terminal amidated analogues of human MGF.

    In this study, MGF / PEG-MGF was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking MGF / PEG-MGF.

  3. 03LabNot a test of MGF / PEG-MGF aloneIn vitro (cell-free)Other

    Low-resolution MS/MS revealed a potentially diagnostic transition (m/z 717.8 to 431.1) that separates C-amidated MGF from the endogenous form.

    In plain wordsIn lab tests, a mass spectrometry signal could tell amidated MGF apart from the body's own form.

    Peptide
    MGF / PEG-MGF
    Outcome
    Not applicableDiagnostic MS/MS transition for C-amidated MGF
    Study

    n: not reported in source

    Outcome group
    Receptor activity and mechanism · Pharmacology

    Source sentences

    Summary
    In addition, low-resolution MS/MS characterization revealed a potentially diagnostic transition (m/z 717.8 → 431.1) for the discrimination of C-amidated MGF from the endogenous form.

    In this study, MGF / PEG-MGF was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking MGF / PEG-MGF.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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