Skip to content

Study · Not a test of the peptide alone · 2011

4 results

Effects of peptides Lys-Glu-Asp-Gly and Ala-Glu-Asp-Gly on hormonal activity and structure of the thyroid gland in hypophysectomized young chickens and old hens.

Kuznik BI, Pateyuk AV, Rusaeva NS, Baranchugova LM, Obydenko VI

Bulletin of experimental biology and medicine1 Feb 2011

PMID22268052 (opens in a new tab)DOI10.1007/s10517-011-1177-3 (opens in a new tab)PepBankPUB-22268052
Publisher pagePubMedAsk about this study
Jump to 4 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone4

In this study, Epitalon was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Epitalon.

  1. 01AnimalNot a test of Epitalon aloneAnimal study (in vivo)Efficacy outcome

    In hypophysectomized birds, 40 days of Lys-Glu-Asp-Gly and Ala-Glu-Asp-Gly administration significantly reduced the degree of hormonal disturbances.

    In plain wordsIn birds with the pituitary gland removed, 40 days of two peptides, Lys-Glu-Asp-Gly and Ala-Glu-Asp-Gly, reduced hormone disturbances.

    Peptide
    Epitalon
    Outcome
    DecreaseHormonal disturbances after hypophysectomy
    Study

    chickenn: not reported in source

    Hypophysectomized young chickens and old hens
    Outcome group
    Thyroid function · Endocrine and hormones

    Source sentences

    Summary
    Administration of peptides Lys-Glu-Asp-Gly and Ala-Glu-Asp-Gly synthesized on the basis the amino acid composition of extracts from the anterior and posterior lobes of the pituitary gland, respectively, to hypophysectomized birds for 40 days significantly reduced the degree of these changes.
    1 context sentence
    Summary · context
    Hypophysectomy in 5-days chickens and old hens was followed by hormonal disturbances and structural changes in the thyroid gland.

    In this study, Epitalon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Epitalon.

  2. 02AnimalNot a test of Epitalon aloneAnimal study (in vivo)Efficacy outcome

    In hypophysectomized birds, 40 days of Lys-Glu-Asp-Gly and Ala-Glu-Asp-Gly administration significantly reduced the degree of structural changes in the thyroid gland.

    In plain wordsIn birds with the pituitary gland removed, 40 days of two peptides, Lys-Glu-Asp-Gly and Ala-Glu-Asp-Gly, reduced structural changes in the thyroid.

    Peptide
    Epitalon
    Outcome
    DecreaseStructural changes in the thyroid gland
    Study

    chickenn: not reported in source

    Hypophysectomized young chickens and old hens
    Outcome group
    Thyroid function · Endocrine and hormones

    Source sentences

    Summary
    Administration of peptides Lys-Glu-Asp-Gly and Ala-Glu-Asp-Gly synthesized on the basis the amino acid composition of extracts from the anterior and posterior lobes of the pituitary gland, respectively, to hypophysectomized birds for 40 days significantly reduced the degree of these changes.
    1 context sentence
    Summary · context
    Hypophysectomy in 5-days chickens and old hens was followed by hormonal disturbances and structural changes in the thyroid gland.

    In this study, Epitalon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Epitalon.

  3. 03AnimalNot a test of Epitalon aloneAnimal study (in vivo)Efficacy outcome

    In old hens, the normalizing effect of the peptides on thyrotrophic hormone concentration was less pronounced than in chickens.

    In plain wordsIn old hens, the peptides normalized thyroid-stimulating hormone less than in young chickens.

    Peptide
    Epitalon
    Outcome
    Direction not reportedThyrotrophic hormone concentration in old hens
    Study

    chickenn: not reported in source

    Hypophysectomized young chickens and old hens
    Outcome group
    Thyroid function · Endocrine and hormones

    Source sentences

    Summary
    The normalizing effect of synthetic peptides on the concentration of thyrotrophic hormone and thyroid hormones in old hens was less pronounced than in chickens.
    1 context sentence
    Summary · context
    Hypophysectomy in 5-days chickens and old hens was followed by hormonal disturbances and structural changes in the thyroid gland.

    In this study, Epitalon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Epitalon.

  4. 04AnimalNot a test of Epitalon aloneAnimal study (in vivo)Efficacy outcome

    In old hens, the normalizing effect of the peptides on thyroid hormone concentrations was less pronounced than in chickens.

    In plain wordsIn old hens, the peptides normalized thyroid hormones less than in young chickens.

    Peptide
    Epitalon
    Outcome
    Direction not reportedThyroid hormone concentration in old hens
    Study

    chickenn: not reported in source

    Hypophysectomized young chickens and old hens
    Outcome group
    Thyroid function · Endocrine and hormones

    Source sentences

    Summary
    The normalizing effect of synthetic peptides on the concentration of thyrotrophic hormone and thyroid hormones in old hens was less pronounced than in chickens.
    1 context sentence
    Summary · context
    Hypophysectomy in 5-days chickens and old hens was followed by hormonal disturbances and structural changes in the thyroid gland.

    In this study, Epitalon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Epitalon.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:47 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

PepBank is a research reference. Talk to a doctor before you use any peptide.