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Study · Ex vivo tissue · 2012

1 result

Modulation of basophil activity: a novel function of the neuropeptide α-melanocyte-stimulating hormone.

Böhm M, Apel M, Sugawara K, Brehler R, Jurk K, Luger TA, Haas H, Paus R, Eiz-Vesper B, Walls AF, Ponimaskin E, Gehring M, Kapp A, Raap U

The Journal of allergy and clinical immunology17 Dec 2011Cited by 22 (Europe PMC)

PMID22178636 (opens in a new tab)DOI10.1016/j.jaci.2011.11.012 (opens in a new tab)PepBankPUB-22178636
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueActivity measurement

    In human basophils, the tripeptide KPV did not suppress basophil activation, unlike α-MSH.

    In plain wordsIn human blood cells in the lab, KPV did not reduce basophil activation.

    Peptide
    KPV
    Outcome
    No significant changeSuppression of basophil activation
    Study

    humann: not reported in source

    basophils from human blood
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    not elicited by the tripeptides KPV and KdPT, both of which lack the central pharmacophore of α-MSH.
    1 context sentence
    Summary · context
    Basophil activity was assessed based on CD63 surface expression and cytokine release.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:56 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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