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Study · Measured the body's own peptide · 2012

6 results

Stimulation of mechano-growth factor expression by myofibrillar proteins in murine myoblasts and myotubes.

Kravchenko IV, Furalyov VA, Popov VO

Molecular and cellular biochemistry9 Dec 2011Cited by 10 (Europe PMC)

PMID22160926 (opens in a new tab)DOI10.1007/s11010-011-1187-5 (opens in a new tab)PepBankPUB-22160926
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study6

No result from this study comes from a test of the peptide.

Natural levels measured6

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelIn vitro (cells)Mechanism

    In murine myoblasts and myotubes, the myofibrillar fraction of skeletal muscle homogenate increased the cells' own MGF expression.

    In plain wordsIn mouse muscle cells, parts of muscle fibre raised the cells' own MGF production.

    Peptide
    MGF / PEG-MGF
    Outcome
    IncreaseMGF expression after myofibrillar fraction
    Study

    mousen: not reported in source

    Murine myoblasts and myotubes
    Outcome group
    Muscle injury and repair · Musculoskeletal

    Source sentences

    Summary
    myofibrillar fraction of skeletal muscle homogenate activated MGF expression in murine myoblasts and myotubes in culture.
    1 context sentence
    Summary · context
    We report here that myofibrillar fraction of skeletal muscle homogenate activated MGF expression in murine myoblasts and myotubes in culture.

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

  2. 02LabEndogenous levelIn vitro (cells)Mechanism

    In murine myoblasts, myomesin was one of three myofibrillar proteins that stimulated MGF synthesis.

    In plain wordsIn mouse muscle cells, the protein myomesin raised the cells' own MGF production.

    Peptide
    MGF / PEG-MGF
    Outcome
    IncreaseMGF expression after myomesin
    Study

    mousen: not reported in source

    Murine myoblasts and myotubes
    Outcome group
    Muscle injury and repair · Musculoskeletal

    Source sentences

    Summary
    Three myofibrillar proteins able to stimulate MGF synthesis were isolated. These proteins were identified by MALDI and immunoblotting as myomesin, myosin-binding protein C, and titin.
    1 context sentence
    Summary · context
    We report here that myofibrillar fraction of skeletal muscle homogenate activated MGF expression in murine myoblasts and myotubes in culture.

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

  3. 03LabEndogenous levelIn vitro (cells)Mechanism

    In murine myoblasts, myosin-binding protein C was one of three myofibrillar proteins that stimulated MGF synthesis.

    In plain wordsIn mouse muscle cells, the protein myosin-binding protein C raised the cells' own MGF production.

    Peptide
    MGF / PEG-MGF
    Outcome
    IncreaseMGF expression after myosin-binding protein C
    Study

    mousen: not reported in source

    Murine myoblasts and myotubes
    Outcome group
    Muscle injury and repair · Musculoskeletal

    Source sentences

    Summary
    Three myofibrillar proteins able to stimulate MGF synthesis were isolated. These proteins were identified by MALDI and immunoblotting as myomesin, myosin-binding protein C, and titin.
    1 context sentence
    Summary · context
    We report here that myofibrillar fraction of skeletal muscle homogenate activated MGF expression in murine myoblasts and myotubes in culture.

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

  4. 04LabEndogenous levelIn vitro (cells)Mechanism

    In murine myoblasts, titin was one of three myofibrillar proteins that stimulated MGF synthesis.

    In plain wordsIn mouse muscle cells, the protein titin raised the cells' own MGF production.

    Peptide
    MGF / PEG-MGF
    Outcome
    IncreaseMGF expression after titin
    Study

    mousen: not reported in source

    Murine myoblasts and myotubes
    Outcome group
    Muscle injury and repair · Musculoskeletal

    Source sentences

    Summary
    Three myofibrillar proteins able to stimulate MGF synthesis were isolated. These proteins were identified by MALDI and immunoblotting as myomesin, myosin-binding protein C, and titin.
    1 context sentence
    Summary · context
    We report here that myofibrillar fraction of skeletal muscle homogenate activated MGF expression in murine myoblasts and myotubes in culture.

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

  5. 05LabEndogenous levelIn vitro (cells)Mechanism

    In the cells, activation of MGF expression was associated with an increase of cAMP level.

    In plain wordsIn mouse muscle cells, the rise in the cells' own MGF went together with a rise in cAMP.

    Peptide
    MGF / PEG-MGF
    Outcome
    IncreasecAMP level with MGF expression
    Study

    mousen: not reported in source

    Murine myoblasts and myotubes
    Outcome group
    Muscle injury and repair · Musculoskeletal

    Source sentences

    Summary
    The activation of MGF expression was associated with the increase of cAMP level in the cells.
    1 context sentence
    Summary · context
    We report here that myofibrillar fraction of skeletal muscle homogenate activated MGF expression in murine myoblasts and myotubes in culture.

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

  6. 06LabEndogenous levelIn vitro (cells)Mechanism

    The adenylyl cyclase inhibitor dideoxyadenosine arrested the stimulation of MGF synthesis by all three myofibrillar proteins.

    In plain wordsIn mouse muscle cells, blocking adenylyl cyclase stopped the rise in the cells' own MGF caused by the three muscle proteins.

    Peptide
    MGF / PEG-MGF
    Outcome
    DecreaseMGF synthesis with adenylyl cyclase inhibitor
    Study

    mousen: not reported in source

    Murine myoblasts and myotubes
    Outcome group
    Muscle injury and repair · Musculoskeletal

    Source sentences

    Summary
    Inhibitor of adenylyl cyclase dideoxyadenosine arrested stimulation of MGF synthesis by all three myofibrillar proteins.
    1 context sentence
    Summary · context
    We report here that myofibrillar fraction of skeletal muscle homogenate activated MGF expression in murine myoblasts and myotubes in culture.

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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