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Study · Not a test of the peptide alone · 2012

6 results

Development and validation of a bioanalytical LC-MS method for the quantification of GHRP-6 in human plasma.

Gil J, Cabrales A, Reyes O, Morera V, Betancourt L, Sánchez A, García G, Moya G, Padrón G, Besada V, González LJ

Journal of pharmaceutical and biomedical analysis15 Nov 2011Cited by 16 (Europe PMC)

PMID22154075 (opens in a new tab)DOI10.1016/j.jpba.2011.11.007 (opens in a new tab)PepBankPUB-22154075
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study6

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone6

In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking GHRP-6.

  1. 01LabNot a test of GHRP-6 aloneIn vitro (cell-free)Other

    The LC-MS method quantified GHRP‑6 in plasma from nine healthy volunteers in a phase I trial.

    In plain wordsIn lab tests, the method measured GHRP‑6 in plasma samples from nine healthy trial volunteers.

    Peptide
    GHRP-6
    Outcome
    Not applicableClinical sample quantification feasibility
    Study

    n = 9

    LC-MS quantification of GHRP-6 in human plasma
    Outcome group
    Analytical methods and detection · Pharmacology

    Source sentences

    Summary
    This method was applied to the quantification of GHRP-6 in plasma from nine healthy volunteers participating in a phase I clinical trial.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

  2. 02LabNot a test of GHRP-6 aloneIn vitro (cell-free)Other

    In human plasma sample processing, cold acetone precipitation recovered GHRP‑6 with a high yield.

    In plain wordsIn lab tests, cold acetone processing recovered GHRP‑6 from human plasma with a high yield.

    Peptide
    GHRP-6
    Outcome
    Not applicableExtraction recovery
    Study

    n: not reported in source

    LC-MS quantification of GHRP-6 in human plasma
    Outcome group
    Analytical methods and detection · Pharmacology

    Source sentences

    Summary
    Sample processing includes a precipitation step with cold acetone to remove the most abundant plasma proteins, recovering the GHRP-6 peptide with a high yield.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

  3. 03LabNot a test of GHRP-6 aloneIn vitro (cell-free)Other

    An LC-MS assay for GHRP‑6 in human plasma had a lower limit of quantification of 5 ng/mL.

    In plain wordsIn lab tests, the assay quantified GHRP‑6 in human plasma down to 5 ng/mL.

    Peptide
    GHRP-6
    Outcome
    Not applicableLower limit of quantification
    Study

    n: not reported in source

    LC-MS quantification of GHRP-6 in human plasma
    Outcome group
    Analytical methods and detection · Pharmacology

    Measurements

    Lower limit of quantification
    5 ng/mL
    human plasma

    Source sentences

    Summary
    The sensitivity of the method was evaluated, establishing the lower limit of quantification at 5 ng/mL and a range for the calibration curve from 5 ng/mL to 50 ng/mL.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

  4. 04LabNot a test of GHRP-6 aloneIn vitro (cell-free)Other

    An LC-MS assay for GHRP‑6 in human plasma used a calibration range from 5 to 50 ng/mL.

    In plain wordsIn lab tests, the assay had a calibration range from 5 to 50 ng/mL for GHRP‑6 in human plasma.

    Peptide
    GHRP-6
    Outcome
    Not applicableCalibration range
    Study

    n: not reported in source

    LC-MS quantification of GHRP-6 in human plasma
    Outcome group
    Analytical methods and detection · Pharmacology

    Measurements

    Calibration range
    5 to 50 ng/mL
    human plasma

    Source sentences

    Summary
    The sensitivity of the method was evaluated, establishing the lower limit of quantification at 5 ng/mL and a range for the calibration curve from 5 ng/mL to 50 ng/mL.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

  5. 05LabNot a test of GHRP-6 aloneIn vitro (cell-free)Other

    Calibration curves for the GHRP‑6 plasma assay had R² values higher than 0.988.

    In plain wordsIn lab tests, GHRP‑6 assay calibration curves had R² values above 0.988.

    Peptide
    GHRP-6
    Outcome
    Not applicableCalibration curve fit
    Study

    n: not reported in source

    LC-MS quantification of GHRP-6 in human plasma
    Outcome group
    Analytical methods and detection · Pharmacology

    Measurements

    Calibration R²
    > 0.988 dimensionless
    calibration curves

    Source sentences

    Summary
    The calibration curves showed R² higher than 0.988.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

  6. 06LabNot a test of GHRP-6 aloneIn vitro (cell-free)Other

    GHRP‑6 remained stable under all tested sample conditions relevant to real-time analyses.

    In plain wordsIn lab tests, GHRP‑6 remained stable under all tested sample conditions relevant to actual analysis.

    Peptide
    GHRP-6
    Outcome
    Not applicableAnalyte stability
    Study

    n: not reported in source

    LC-MS quantification of GHRP-6 in human plasma
    Outcome group
    Analytical methods and detection · Pharmacology

    Source sentences

    Summary
    The stability of the analyte and its internal standard (IS) was demonstrated in all conditions the samples would experience in a real time analyses.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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