Skip to content

Study · Randomized controlled trial · n = 96 · 2012

1 result

Intranasal oxytocin and salivary cortisol concentrations during social rejection in university students.

Linnen AM, Ellenbogen MA, Cardoso C, Joober R

Stress (Amsterdam, Netherlands)20 Dec 2011Cited by 78 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. 1 result from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In undergraduate students, a single dose of intranasal oxytocin decreased salivary cortisol during a social rejection stressor relative to placebo.

    In plain wordsIn university students, nasal oxytocin lowered saliva cortisol during a social rejection task, compared with placebo.

    Peptide
    Oxytocin
    Outcome
    DecreaseSalivary cortisol during social rejection stressor
    Study

    n = 96

    Comparator
    Placebo
    Outcome group
    Stress hormones · Endocrine and hormones
    Studied dose
    24 IU · intranasalAs given in this study (human).

    Source sentences

    Summary
    Participants who were administered oxytocin exhibited a decrease in cortisol levels, relative to placebo, during the YIPS, F (4, 184)=4.50, p<0.05.
    2 context sentences
    Summary · context
    Ninety-six undergraduate students underwent the YIPS, where participants were excluded from two separate conversations by two same-sex confederates.
    Summary · context
    Participants were administered, in a double-blind design, a single dose of intranasal oxytocin (24 IU) or placebo prior to beginning the YIPS.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.