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Study · Randomized controlled trial · n = 47 · 2012

2 results

Intranasal oxytocin enhances emotion recognition from dynamic facial expressions and leaves eye-gaze unaffected.

Lischke A, Berger C, Prehn K, Heinrichs M, Herpertz SC, Domes G

Psychoneuroendocrinology19 Sept 2011Cited by 162 (Europe PMC)

PMID21862223 (opens in a new tab)DOI10.1016/j.psyneuen.2011.07.015 (opens in a new tab)PepBankPUB-21862223
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In participants, intranasal oxytocin had no effect on visual scanning of emotional faces compared with placebo.

    In plain wordsIn study participants, nasal oxytocin did not change where they looked on emotional faces, compared with placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changeVisual scanning of emotional faces (eye region)
    Study

    n = 47

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    24 IU · intranasalAs given in this study (human).

    Source sentences

    Summary
    Although oxytocin administration had no effect on participants' visual scanning of emotional faces
    1 context sentence
    Summary · context
    In a double-blind, placebo-controlled between-subjects design participants received 24 IU intranasal oxytocin (n = 23) or a placebo (n = 24).
  2. 02HumanRandomized controlled trialEfficacy outcome

    In participants, intranasal oxytocin enhanced facial emotion recognition, with emotions recognised at lower intensity than with placebo.

    In plain wordsIn study participants, nasal oxytocin helped them recognise emotions in faces at lower intensity than placebo did.

    Peptide
    Oxytocin
    Outcome
    IncreaseEmotion recognition performance in dynamic facial expressions
    Study

    n = 47

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    24 IU · intranasalAs given in this study (human).

    Source sentences

    Summary
    it generally enhanced recognition performance, as the oxytocin group recognized emotional expressions at lower intensity levels.
    1 context sentence
    Summary · context
    In a double-blind, placebo-controlled between-subjects design participants received 24 IU intranasal oxytocin (n = 23) or a placebo (n = 24).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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