In healthy men with exercise-induced muscle damage, a single therapeutic ultrasound treatment did not change gene expression of the three IGF-1 splice variants, including mechano growth factor.
In plain wordsIn healthy men with damaged muscle, one ultrasound treatment did not change the body's own mechano growth factor gene expression.
- Peptide
- MGF / PEG-MGF
- Outcome
- No significant changeIGF-1 splice variant gene expression after therapeutic ultrasound in damaged muscle
- Study
n: not reported in source
- Comparator
- No ultrasound effect, damaged muscle
- Outcome group
- Muscle injury and repair · Musculoskeletal
Source sentences
In damaged skeletal muscle, no significant change in gene expression attributable to TUS was determined.
3 context sentences(design, population, supporting numbers)
A single treatment of TUS in damaged muscle induces no change in the gene expression of the 3 IGF-1 splice variants in humans.
Sixteen healthy men (18-29 years of age), physically active, were randomized to either a control (CON) or experimental group (EXP).
Both groups received TUS, delivered for 10 minutes on a standardized area of the vastus lateralis of only 1 leg (1.0 MHz, 1.5 W/cm(2)).
This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.