Attenuation of luteolytic response following fish meal supplementation in dairy buffaloes (Bubalus bubalis).

Malik AA, Gandotra VK, Brar PS, Ghuman SP, Dhaliwal GS

Animal reproduction science11 May 2011Cited by 4 (Europe PMC)

PMID21641133DOI10.1016/j.anireprosci.2011.04.010PepBankPUB-21641133

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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study6

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone6

In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Oxytocin.

01AnimalNot a test of Oxytocin aloneAnimal study (in vivo)Efficacy outcome
In dairy buffaloes challenged with oxytocin, fish meal supplementation lowered peak PGFM concentration versus control.
In plain wordsIn buffaloes, a fish meal supplement lowered the prostaglandin response to an oxytocin challenge compared with unsupplemented buffaloes.
Peptide
Oxytocin
Outcome
DecreasePeak PGFM concentration 1 h after oxytocin challenge
Study
Buffalo (Bubalus bubalis)n = 12
Murrah buffaloes with oxytocin challenge
Comparator
Non-supplemented control
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Measurements
PGFM, fish meal group
197.4 pg/ml
1h post-OT
PGFM, control
326.3 pg/ml
1h post-OT
Source sentences
Summary
During peak response (1h post-OT challenge), PGFM concentration was significantly lower (P<0.05) in FM supplemented buffaloes than in the control (197.4±41.7pg/ml versus 326.3±33.5pg/ml, respectively).
2 context sentences(design, population, supporting numbers)
Summary · context
Five cycling Murrah buffaloes were supplemented with 250g FM daily for 55 days in addition to their routine feed and seven buffaloes were kept as non-supplemented control.
Summary · context
On day 15 of synchronized cycle, animals were challenged with oxytocin (OT; 100IU) intravenously and blood samples were collected at 15min interval, 1h before to 4h after OT challenge.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-2164113301
02AnimalNot a test of Oxytocin aloneAnimal study (in vivo)Efficacy outcome
In dairy buffaloes challenged with oxytocin, mean hourly PGFM concentration was lower with fish meal than in controls at all occasions.
In plain wordsIn buffaloes, a fish meal supplement kept hourly prostaglandin levels lower than in controls after an oxytocin challenge.
Peptide
Oxytocin
Outcome
DecreaseMean hourly PGFM concentration after oxytocin challenge
Study
Buffalo (Bubalus bubalis)n = 12
Murrah buffaloes with oxytocin challenge
Comparator
Non-supplemented control
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
The mean hourly concentration of PGFM in FM supplemented buffaloes was lower than in the control buffaloes at all the occasions.
2 context sentences(design, population, supporting numbers)
Summary · context
Five cycling Murrah buffaloes were supplemented with 250g FM daily for 55 days in addition to their routine feed and seven buffaloes were kept as non-supplemented control.
Summary · context
On day 15 of synchronized cycle, animals were challenged with oxytocin (OT; 100IU) intravenously and blood samples were collected at 15min interval, 1h before to 4h after OT challenge.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-2164113302
03AnimalNot a test of Oxytocin aloneAnimal study (in vivo)Efficacy outcome
In dairy buffaloes challenged with oxytocin, the percent rise in PGFM was smaller with fish meal than in controls.
In plain wordsIn buffaloes, the prostaglandin rise after an oxytocin challenge was smaller with fish meal than in controls.
Peptide
Oxytocin
Outcome
DecreasePercent rise in PGFM after oxytocin challenge
Study
Buffalo (Bubalus bubalis)n = 12
Murrah buffaloes with oxytocin challenge
Comparator
Non-supplemented control
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Measurements
PGFM rise, fish meal group
11.73%
after OT
PGFM rise, control
22.47%
after OT
Source sentences
Summary
Also the percent rise in PGFM after OT-challenge in FM supplemented buffaloes was less than the control (11.73% versus 22.47%).
2 context sentences(design, population, supporting numbers)
Summary · context
Five cycling Murrah buffaloes were supplemented with 250g FM daily for 55 days in addition to their routine feed and seven buffaloes were kept as non-supplemented control.
Summary · context
On day 15 of synchronized cycle, animals were challenged with oxytocin (OT; 100IU) intravenously and blood samples were collected at 15min interval, 1h before to 4h after OT challenge.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-2164113303
04AnimalNot a test of Oxytocin aloneAnimal study (in vivo)Efficacy outcome
In dairy buffaloes, fish meal supplementation did not affect the size of the corpus luteum.
In plain wordsIn buffaloes, a fish meal supplement did not change the size of the corpus luteum.
Peptide
Oxytocin
Outcome
No significant changeCorpus luteum size
Study
Buffalo (Bubalus bubalis)n = 12
Murrah buffaloes with oxytocin challenge
Comparator
Non-supplemented control
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
The dietary supplementation did not affect the size of corpus luteum (CL)
2 context sentences(design, population, supporting numbers)
Summary · context
Five cycling Murrah buffaloes were supplemented with 250g FM daily for 55 days in addition to their routine feed and seven buffaloes were kept as non-supplemented control.
Summary · context
On day 15 of synchronized cycle, animals were challenged with oxytocin (OT; 100IU) intravenously and blood samples were collected at 15min interval, 1h before to 4h after OT challenge.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-2164113304
05AnimalNot a test of Oxytocin aloneAnimal study (in vivo)Efficacy outcome
In dairy buffaloes, fish meal supplementation did not affect plasma progesterone concentration.
In plain wordsIn buffaloes, a fish meal supplement did not change progesterone levels in the blood.
Peptide
Oxytocin
Outcome
No significant changePlasma progesterone concentration
Study
Buffalo (Bubalus bubalis)n = 12
Murrah buffaloes with oxytocin challenge
Comparator
Non-supplemented control
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
The dietary supplementation did not affect the size of corpus luteum (CL) and plasma progesterone concentration.
2 context sentences(design, population, supporting numbers)
Summary · context
Five cycling Murrah buffaloes were supplemented with 250g FM daily for 55 days in addition to their routine feed and seven buffaloes were kept as non-supplemented control.
Summary · context
On day 15 of synchronized cycle, animals were challenged with oxytocin (OT; 100IU) intravenously and blood samples were collected at 15min interval, 1h before to 4h after OT challenge.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-2164113305
06AnimalNot a test of Oxytocin aloneAnimal study (in vivo)Safety outcome
In dairy buffaloes, plasma glucose and total protein stayed within normal physiological limits during fish meal supplementation.
In plain wordsIn buffaloes given fish meal, blood glucose and total protein stayed within normal limits.
Peptide
Oxytocin
Outcome
No significant changePlasma glucose and total protein
Study
Buffalo (Bubalus bubalis)n = 12
Murrah buffaloes with oxytocin challenge
Comparator
Non-supplemented control
Outcome group
Adverse events · Metabolic and weight
Source sentences
Summary
Plasma glucose and total protein concentrations remained within the normal physiological limits during FM supplementation.
2 context sentences(design, population, supporting numbers)
Summary · context
Five cycling Murrah buffaloes were supplemented with 250g FM daily for 55 days in addition to their routine feed and seven buffaloes were kept as non-supplemented control.
Summary · context
On day 15 of synchronized cycle, animals were challenged with oxytocin (OT; 100IU) intravenously and blood samples were collected at 15min interval, 1h before to 4h after OT challenge.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-2164113306

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
11 Oct 2026, 01:30 UTC
Study results updated
Version 1
9 Oct 2026, 02:52 UTC
First added · source update from Europe PMC

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