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Study · Measured the body's own peptide · 2011

3 results

Effect of eccentric exercise velocity on akt/mtor/p70(s6k) signaling in human skeletal muscle.

Roschel H, Ugrinowistch C, Barroso R, Batista MA, Souza EO, Aoki MS, Siqueira-Filho MA, Zanuto R, Carvalho CR, Neves M, Mello MT, Tricoli V

Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme1 Apr 2011Cited by 18 (Europe PMC)

PMID21609291 (opens in a new tab)DOI10.1139/h10-111 (opens in a new tab)PepBankPUB-21609291
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelNon-randomized trialMechanism

    In healthy adults after eccentric knee extensions, muscle MGF mRNA was similar between the slow and fast exercise velocity groups.

    In plain wordsIn adults after leg exercise, the body's own MGF levels in muscle were similar after slow and fast eccentric exercise.

    Peptide
    MGF / PEG-MGF
    Outcome
    No significant changeMGF mRNA, slow versus fast eccentric exercise
    Study

    n = 20

    Comparator
    Fast versus slow eccentric exercise
    Outcome group
    Muscle injury and repair · Musculoskeletal

    Source sentences

    Summary
    MGF messenger RNA was similar between groups
    2 context sentences
    Summary · context
    Twenty subjects were assigned to either a slow (20°·s(-1); ES) or fast EE (210°·s(-1); EF) group.
    Summary · context
    Biopsies were taken from vastus lateralis at baseline (B), immediately after (T1), and 2 h after (T2) the completion of 5 sets of 8 repetitions of eccentric knee extensions.

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelNon-randomized trialMechanism

    In the slow eccentric exercise group, muscle MGF mRNA was significantly higher 2 h after exercise than at baseline.

    In plain wordsIn adults doing slow leg exercise, the body's own MGF level in muscle was higher 2 hours after exercise than before.

    Peptide
    MGF / PEG-MGF
    Outcome
    IncreaseMGF mRNA at 2 h versus baseline, slow group
    Study

    n: not reported in source

    Comparator
    Baseline
    Outcome group
    Muscle injury and repair · Musculoskeletal

    Source sentences

    Summary
    and only significantly higher at T2 than at B in ES.
    2 context sentences
    Summary · context
    Twenty subjects were assigned to either a slow (20°·s(-1); ES) or fast EE (210°·s(-1); EF) group.
    Summary · context
    Biopsies were taken from vastus lateralis at baseline (B), immediately after (T1), and 2 h after (T2) the completion of 5 sets of 8 repetitions of eccentric knee extensions.

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelNon-randomized trialMechanism

    In the fast eccentric exercise group, muscle MGF mRNA was not significantly higher 2 h after exercise than at baseline.

    In plain wordsIn adults doing fast leg exercise, the body's own MGF level in muscle did not rise significantly 2 hours after exercise.

    Peptide
    MGF / PEG-MGF
    Outcome
    No significant changeMGF mRNA at 2 h versus baseline, fast group
    Study

    n: not reported in source

    Comparator
    Baseline
    Outcome group
    Muscle injury and repair · Musculoskeletal

    Source sentences

    Summary
    and only significantly higher at T2 than at B in ES.
    2 context sentences
    Summary · context
    Twenty subjects were assigned to either a slow (20°·s(-1); ES) or fast EE (210°·s(-1); EF) group.
    Summary · context
    Biopsies were taken from vastus lateralis at baseline (B), immediately after (T1), and 2 h after (T2) the completion of 5 sets of 8 repetitions of eccentric knee extensions.

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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