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Study · Measured the body's own peptide · 1992

5 results

The distribution and development of delta sleep-inducing Peptide-like immunoreactivity in postnatal and prepubertal Guinea-pig brain.

Pu LP, Dubois PM

Journal of neuroendocrinology1 Feb 1992

PMID21554575 (opens in a new tab)DOI10.1111/j.1365-2826.1992.tb00343.x (opens in a new tab)PepBankPUB-21554575
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

No result from this study comes from a test of the peptide.

Natural levels measured5

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In 2- to 60-day-old guinea pigs, DSIP-immunoreactive perikarya were seen in the olfactory bulb and tubercle, diagonal band of Broca, septum, preoptic area, hypothalamus, arcuate nucleus and hippocampus.

    In plain wordsIn guinea pigs, natural DSIP-like material was found in nerve cell bodies in many brain regions.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableDSIP-immunoreactive perikarya in guinea pig brain
    Study

    guinea pign: not reported in source

    brain sections
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    DSIP-immunoreactive perikarya were observed in the olfactory bulb and tubercle, diagonal band of Broca, septum, preoptic area, anterior and lateral hypothalamus, arcuate nucleus and hippocampus.
    1 context sentence
    Summary · context
    The distribution and development of delta sleep-inducing peptide (DSIP) in the guinea-pig brain were studied in 2- to 60-day-old animals by using the indirect immunofluorescence method.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In guinea pigs, DSIP-immunoreactive fibres were widely located from forebrain to mesencephalon, with the densest innervation in the median eminence.

    In plain wordsIn guinea pigs, natural DSIP-like fibres ran from the forebrain to the midbrain and were densest in the median eminence.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableDSIP-immunoreactive fibres in guinea pig brain
    Study

    guinea pign: not reported in source

    brain sections
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    In addition to the densest innervation of the median eminence, DSIP-immunoreactive fibres were widely localized from forebrain to mesencephalon.
    1 context sentence
    Summary · context
    The distribution and development of delta sleep-inducing peptide (DSIP) in the guinea-pig brain were studied in 2- to 60-day-old animals by using the indirect immunofluorescence method.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Other

    In guinea pigs, the topographic distribution pattern of DSIP-immunolabelled neuronal elements seemed similar throughout development.

    In plain wordsIn guinea pigs, the places where natural DSIP-like material was found stayed much the same during growth.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableTopographic distribution of DSIP-immunolabelled elements across development
    Study

    guinea pign: not reported in source

    brain sections
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Furthermore, throughout development the topographic distribution pattern of immunolabelled neuronal elements seemed to be similar.
    1 context sentence
    Summary · context
    The distribution and development of delta sleep-inducing peptide (DSIP) in the guinea-pig brain were studied in 2- to 60-day-old animals by using the indirect immunofluorescence method.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  4. 04AnimalEndogenous levelAnimal study (in vivo)Other

    In guinea pigs, a generalized increase in number, immunofluorescence intensity and varicosities of DSIP fibres appeared with growth.

    In plain wordsIn guinea pigs, natural DSIP-like fibres became more numerous and brighter as the animals grew.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseNumber, intensity and varicosities of DSIP fibres with growth
    Study

    guinea pign: not reported in source

    brain sections
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    However, a generalized increase in number, immunofluorescence intensity and varicosities of DSIP fibres was displayed with the growth.
    1 context sentence
    Summary · context
    The distribution and development of delta sleep-inducing peptide (DSIP) in the guinea-pig brain were studied in 2- to 60-day-old animals by using the indirect immunofluorescence method.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  5. 05AnimalEndogenous levelAnimal study (in vivo)Other

    In guinea pigs, the field of DSIP-immunoreactive fibre endings appeared to be close to the blood vessels of the brain, the ventricles, the subarachnoid space or immunolabelled perikarya.

    In plain wordsIn guinea pigs, natural DSIP-like fibre endings seemed to lie close to brain blood vessels, fluid spaces or labelled nerve cell bodies.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicablePosition of DSIP-immunoreactive fibre endings
    Study

    guinea pign: not reported in source

    brain sections
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    The field of immunoreactive fibre endings appeared to be in close association with either the blood vessels of brain, ventricles, subarachnoid space or immunolabelled perikarya.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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