In rats, stimulation of mu-opioid receptors in the nucleus accumbens core reversed the suppression of intake that third-ventricle MTII caused.
In plain wordsIn rats, stimulating opioid receptors in one brain region reversed the reduced eating that MTII caused.
- Peptide
- Melanotan II
- Outcome
- IncreaseReversal of MTII-induced intake suppression by MOR stimulation
- Study
ratn: not reported in source
nucleus accumbens core MOR stimulation- Outcome group
- Appetite and food intake · Metabolic and weight
Source sentences
Suppression of intake caused by MTII was reversed by MOR stimulation.
1 context sentence(design, population, supporting numbers)
In experiment 3, we determined whether MOR activation in the NAcc core could attenuate satiety-related signaling caused by infusion of the melanocortin agonist MTII into the third ventricle.
In this study, Melanotan II was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Melanotan II.