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Study · Randomized controlled trial · n = 56 · 2011

2 results

Oxytocin increases recognition of masked emotional faces.

Schulze L, Lischke A, Greif J, Herpertz SC, Heinrichs M, Domes G

Psychoneuroendocrinology7 Apr 2011Cited by 134 (Europe PMC)

PMID21477929 (opens in a new tab)DOI10.1016/j.psyneuen.2011.03.011 (opens in a new tab)PepBankPUB-21477929
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In healthy adults, a single intranasal oxytocin dose enhanced detection accuracy of briefly presented emotional faces compared with placebo.

    In plain wordsIn healthy adults, nasal oxytocin improved detecting briefly shown emotional faces compared with placebo.

    Peptide
    Oxytocin
    Outcome
    IncreaseDetection accuracy of briefly presented emotional faces (d')
    Study

    n = 56

    Comparator
    Placebo
    Outcome group
    Anxiety and mood · Mental health and mood
    Studied dose
    Dose not stated · intranasal · single doseAs given in this study (human).

    Source sentences

    Summary
    Discrimination indices (d') showed that oxytocin generally enhanced detection accuracy of emotional stimuli.
    1 context sentence
    Summary · context
    Fifty-six participants were administered intranasal oxytocin or a placebo in a double-blind, randomized, between-subjects design.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In healthy adults, the oxytocin enhancement of detection accuracy was more pronounced for happy faces than for angry faces.

    In plain wordsIn healthy adults, the boost from nasal oxytocin was larger for spotting happy faces.

    Peptide
    Oxytocin
    Outcome
    IncreaseDetection of happy faces
    Study

    n = 56

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Mental health and mood
    Studied dose
    Dose not stated · intranasal · single doseAs given in this study (human).

    Source sentences

    Summary
    This effect was more pronounced for the recognition of happy faces.
    1 context sentence
    Summary · context
    Fifty-six participants were administered intranasal oxytocin or a placebo in a double-blind, randomized, between-subjects design.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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