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Study · Not a test of the peptide alone · 2011

2 results

Dissolving microneedle patch for transdermal delivery of human growth hormone.

Lee JW, Choi SO, Felner EI, Prausnitz MR

Small (Weinheim an der Bergstrasse, Germany)4 Jan 2011Cited by 194 (Europe PMC)

PMID21360810 (opens in a new tab)PMCIDPMC4143249 (opens in a new tab)DOI10.1002/smll.201001091 (opens in a new tab)PepBankPUB-21360810
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, HGH (somatotropin) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking HGH (somatotropin).

  1. 01AnimalNot a test of HGH (somatotropin) aloneAnimal study (in vivo)Pharmacokinetics

    In hairless rats, growth hormone delivered with dissolving microneedles had pharmacokinetics similar to conventional subcutaneous injection.

    In plain wordsIn hairless rats, growth hormone delivered with dissolving microneedles had drug exposure similar to conventional subcutaneous injection.

    Peptide
    HGH (somatotropin)
    Outcome
    Direction not reportedPharmacokinetics
    Study

    ratn: not reported in source

    Hairless rats
    Comparator
    Conventional subcutaneous injection
    Outcome group
    Pharmacokinetics · Pharmacology

    Source sentences

    Summary
    After manual insertion into the skin of hairless rats, hGH pharmacokinetics were similar to conventional subcutaneous injection.

    In this study, HGH (somatotropin) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking HGH (somatotropin).

  2. 02AnimalNot a test of HGH (somatotropin) aloneAnimal study (in vivo)Safety outcome

    In hairless rats, the growth hormone microneedle patch caused only slight, transient erythema and was well tolerated.

    In plain wordsIn hairless rats, the growth hormone microneedle patch caused only slight, temporary skin redness.

    Peptide
    HGH (somatotropin)
    Outcome
    Not applicableTransient erythema
    Study

    ratn: not reported in source

    Hairless rats
    Outcome group
    Adverse events · Skin and wound

    Source sentences

    Summary
    The dissolving microneedle patch was well tolerated, causing only slight, transient erythema.
    1 context sentence
    Summary · context
    After manual insertion into the skin of hairless rats, hGH pharmacokinetics were similar to conventional subcutaneous injection.

    In this study, HGH (somatotropin) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking HGH (somatotropin).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:36 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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