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Study · Measured the body's own peptide · 2011

2 results

Differential involvement of noradrenaline and nitric oxide in the regulation of vasopressin and oxytocin expression in rat supraoptic nucleus.

Raison D, Hardin-Pouzet H, Grange-Messent V

Journal of neuroscience research22 Feb 2011Cited by 2 (Europe PMC)

PMID21344477 (opens in a new tab)DOI10.1002/jnr.22568 (opens in a new tab)PepBankPUB-21344477
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelEx vivo tissueMechanism

    In perfused rat hypothalamic slices, noradrenaline was involved early in regulating expression of neuropeptides including oxytocin.

    In plain wordsIn rat brain slices, noradrenaline helped control early on how much of the body's own oxytocin was made.

    Peptide
    Oxytocin
    Outcome
    Not applicableNoradrenaline regulation of oxytocin expression
    Study

    ratn: not reported in source

    Perfused rat hypothalamic slices (supraoptic nucleus)
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones

    Source sentences

    Summary
    NA is involved early in the regulation of the expression of neuropeptides, including vasopressin (AVP) and oxytocin (OT).
    1 context sentence
    Summary · context
    Slices of rat hypothalamus maintained ex vivo by perfusion were used to study the short-term involvement of noradrenaline (NA) and nitric oxide (NO) in the mechanisms of chemical plasticity of the SON.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02LabEndogenous levelEx vivo tissueMechanism

    In rat supraoptic nucleus, nitric oxide was involved in the signalling pathway regulating vasopressin expression but not oxytocin expression.

    In plain wordsIn rat brain slices, nitric oxide helped control vasopressin but not the body's own oxytocin.

    Peptide
    Oxytocin
    Outcome
    No significant changeNitric oxide involvement in oxytocin expression
    Study

    ratn: not reported in source

    Perfused rat hypothalamic slices (supraoptic nucleus)
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones

    Source sentences

    Summary
    in the SON, NO is involved in the signaling pathway regulating the expression of AVP but not that of OT.
    1 context sentence
    Summary · context
    Slices of rat hypothalamus maintained ex vivo by perfusion were used to study the short-term involvement of noradrenaline (NA) and nitric oxide (NO) in the mechanisms of chemical plasticity of the SON.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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