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Study · Measured the body's own peptide · 2011

3 results

Changes in salivary antimicrobial peptides, immunoglobulin A and cortisol after prolonged strenuous exercise.

Usui T, Yoshikawa T, Orita K, Ueda SY, Katsura Y, Fujimoto S, Yoshimura M

European journal of applied physiology20 Jan 2011Cited by 33 (Europe PMC)

PMID21249386 (opens in a new tab)DOI10.1007/s00421-011-1830-6 (opens in a new tab)PepBankPUB-21249386
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelNon-randomized trialOther

    In young male volunteers, saliva LL‑37 concentration was increased during and after a 60-min session of strenuous exercise compared with a resting session.

    In plain wordsIn young men, prolonged hard exercise raised the body's own LL‑37 level in saliva compared with rest.

    Peptide
    LL-37
    Outcome
    IncreaseSaliva LL-37 concentration
    Study

    n = 10

    Comparator
    Resting session (sat quietly)
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    Saliva HBD-2 and LL-37 concentrations and secretion rates were increased during and after the exercise, whereas saliva IgA concentration and secretion rates were decreased after the exercise.
    2 context sentences
    Summary · context
    Ten young male volunteers either exercised on recumbent ergometer at 75% [Formula: see text] for 60 min (exercise session) or sat quietly (resting session).
    Summary · context
    Saliva samples were obtained at 60-min intervals during sessions for measurements of saliva antimicrobial components (HBD-2, LL-37, and IgA), saliva cortisol and osmolality.

    This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelNon-randomized trialOther

    In young male volunteers, the saliva LL‑37 secretion rate was increased during and after a 60-min session of strenuous exercise compared with a resting session.

    In plain wordsIn young men, prolonged hard exercise raised the rate at which the body's own LL‑37 was released into saliva, compared with rest.

    Peptide
    LL-37
    Outcome
    IncreaseSaliva LL-37 secretion rate
    Study

    n = 10

    Comparator
    Resting session (sat quietly)
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    Saliva HBD-2 and LL-37 concentrations and secretion rates were increased during and after the exercise, whereas saliva IgA concentration and secretion rates were decreased after the exercise.
    2 context sentences
    Summary · context
    Ten young male volunteers either exercised on recumbent ergometer at 75% [Formula: see text] for 60 min (exercise session) or sat quietly (resting session).
    Summary · context
    Saliva samples were obtained at 60-min intervals during sessions for measurements of saliva antimicrobial components (HBD-2, LL-37, and IgA), saliva cortisol and osmolality.

    This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelNon-randomized trialOther

    In young male volunteers, the area under the curve of saliva LL‑37 over time was negatively correlated with that of saliva cortisol.

    In plain wordsIn young men, higher saliva cortisol over time was linked to lower body's own LL‑37 in saliva.

    Peptide
    LL-37
    Outcome
    DecreaseCorrelation of saliva LL-37 with saliva cortisol
    Study

    n = 10

    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    The areas under the curve of the time courses of saliva levels of HBD-2 and LL-37 were negatively correlated with those of cortisol levels in saliva.
    2 context sentences
    Summary · context
    Ten young male volunteers either exercised on recumbent ergometer at 75% [Formula: see text] for 60 min (exercise session) or sat quietly (resting session).
    Summary · context
    Saliva samples were obtained at 60-min intervals during sessions for measurements of saliva antimicrobial components (HBD-2, LL-37, and IgA), saliva cortisol and osmolality.

    This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:58 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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