In healthy men with impaired emotion regulation ability, intranasal oxytocin reduced the cortisol response to a social stressor, whereas placebo was followed by an increased response.
In plain wordsIn healthy young men with poor emotion regulation, nasal oxytocin lowered the stress cortisol response; after placebo it rose.
- Peptide
- Oxytocin
- Outcome
- DecreaseCortisol response to public speaking stressor in individuals with low emotion regulation ability
- Study
n: not reported in source
- Comparator
- Placebo
- Outcome group
- Anxiety and mood · Endocrine and hormones
- Studied dose
- 24 IU · intranasalAs given in this study (human).
Source sentences
Individuals with impaired ERA showed a reduced cortisol response to stress after oxytocin but an increased cortisol response after placebo application.
2 context sentences(design, population, supporting numbers)
In a double-blind study thirty-six healthy male students with either high or low ERA were randomly assigned to receive intranasally 24 IU oxytocin or placebo.
Cortisol was measured at several times before and after a social stressor (public speaking).