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Study · Animal study (in vivo) · mouse · 2010

1 result

[Investigation of anti-hypoxic action of 3-hydroxypyridine derivatives in animals with some types of experimental pathology].

Iasnetsov VV, Ivanov IuV, Karsanova SK, Chel'naia NA, Skachilova SIa, Savina NV, Solov'ev NA, Filipenko TV, Luk'ianov VN

Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine1 May 2010

PMID21033401 (opens in a new tab)PepBankPUB-21033401

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In mice with carotid artery occlusion, a single injection of semax had an anti-hypoxic action in acute normobaric hypoxia with hypercapnia.

    In plain wordsIn mice with a blocked neck artery, one semax injection protected against low oxygen with raised carbon dioxide.

    Peptide
    Semax
    Outcome
    IncreaseAnti-hypoxic action in acute normobaric hypoxia with hypercapnia
    Study

    mousen: not reported in source

    Common carotid artery occlusion, acute normobaric hypoxia with hypercapnia
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated · single injectionAs given in this study (mouse).

    Source sentences

    Summary
    Experiments with occlusion of the common carotid artery in mice demonstrated that, unlike mexidol and SK-170, single injection of new derivatives of 3-hydroxypyridine (3-HP) SK-100 and IBKhF-2, and semax have an anti-hypoxic action on the model of acute normobaric hypoxia with hypercapnia.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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