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Study · Randomized controlled trial · 2010

3 results

Oxytocin decreases aversion to angry faces in an associative learning task.

Evans S, Shergill SS, Averbeck BB

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology15 Sept 2010Cited by 65 (Europe PMC)

PMID20844475 (opens in a new tab)PMCIDPMC2978766 (opens in a new tab)DOI10.1038/npp.2010.110 (opens in a new tab)PepBankPUB-20844475
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In study participants, oxytocin specifically decreased aversion to angry faces in a face-reward learning task.

    In plain wordsIn study participants, oxytocin reduced the tendency to avoid angry faces in a learning task.

    Peptide
    Oxytocin
    Outcome
    DecreaseAversion to angry faces in an associative learning task
    Study

    n: not reported in source

    Outcome group
    Social behavior and cognition · Mental health and mood
    Studied dose
    Dose not stated

    Source sentences

    Summary
    We found that oxytocin specifically decreased aversion to angry faces, without affecting integration of positive or negative financial feedback or choices related to happy vs sad faces.
    1 context sentence
    Summary · context
    Thus, we examined the hypothesis that oxytocin would specifically affect social and not financial information in a decision making task, in which participants learned which of the two faces, one smiling and the other angry or sad, was most often being rewarded.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In study participants, oxytocin did not affect integration of positive or negative financial feedback.

    In plain wordsIn study participants, oxytocin did not change how money gains and losses were used in the task.

    Peptide
    Oxytocin
    Outcome
    No significant changeIntegration of positive or negative financial feedback
    Study

    n: not reported in source

    Outcome group
    Social behavior and cognition · Mental health and mood
    Studied dose
    Dose not stated

    Source sentences

    Summary
    without affecting integration of positive or negative financial feedback
    1 context sentence
    Summary · context
    Thus, we examined the hypothesis that oxytocin would specifically affect social and not financial information in a decision making task, in which participants learned which of the two faces, one smiling and the other angry or sad, was most often being rewarded.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In study participants, oxytocin did not affect choices related to happy versus sad faces.

    In plain wordsIn study participants, oxytocin did not change choices between happy and sad faces.

    Peptide
    Oxytocin
    Outcome
    No significant changeChoices between happy and sad faces
    Study

    n: not reported in source

    Outcome group
    Social behavior and cognition · Mental health and mood
    Studied dose
    Dose not stated

    Source sentences

    Summary
    choices related to happy vs sad faces.
    1 context sentence
    Summary · context
    Thus, we examined the hypothesis that oxytocin would specifically affect social and not financial information in a decision making task, in which participants learned which of the two faces, one smiling and the other angry or sad, was most often being rewarded.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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