In post-mortem hypothalamus of patients with Huntington disease, the number of oxytocin-expressing neurons was 45% lower than in healthy controls.
In plain wordsHuntington disease was linked to fewer of the body's own oxytocin-producing brain cells, 45% fewer than in healthy controls.
- Peptide
- Oxytocin
- Outcome
- DecreaseNumber of oxytocin-expressing hypothalamic neurons in Huntington disease
- Study
n: not reported in source
- Comparator
- Healthy controls
- Outcome group
- Neuroprotection · Nervous system and cognition
Measurements
- Decrease in oxytocin-expressing neurons
- 45%
- Huntington disease
Source sentences
Both oxytocin- and vasopressin-expressing neurons were decreased by 45 and 24%, respectively, while the number of cocaine- and amphetamine-regulated transcript (CART)-expressing neurons was increased by 30%.
1 context sentence(design, population, supporting numbers)
In this study, we quantified the neuropeptide-expressing hypothalamic neurons known to regulate metabolism and emotion in patients with HD compared to healthy controls using unbiased stereological methods.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.