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Study · Not a test of the peptide alone · 2010

3 results

[Effects of hypophyseal Lys-Glu-Asp-Gly and Ala-Glu-Asp-Gly synthetic peptides on immunity, hemostasis, morphology and functions of the thyroid gland in neonatally hypophysectomized chicken and one-year-old birds].

Kuznik BI, Pateiuk AV, Rusaeva NS, Baranchugova LM, Obydenko VI

Patologicheskaia fiziologiia i eksperimental'naia terapiia1 Jan 2010

PMID20731122 (opens in a new tab)PepBankPUB-20731122
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, Epitalon was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Epitalon.

  1. 01AnimalNot a test of Epitalon aloneAnimal study (in vivo)Efficacy outcome

    In hypophysectomized birds, the injected peptides Lys-Glu-Asp-Gly and Ala-Glu-Asp-Gly prevented atrophic changes of the thyroid gland.

    In plain wordsIn birds with the pituitary gland removed, the two injected peptides prevented shrinking of the thyroid gland.

    Peptide
    Epitalon
    Outcome
    DecreaseAtrophic changes of the thyroid gland
    Study

    chickenn: not reported in source

    Hypophysectomized chicken and one-year-old birds
    Outcome group
    Thyroid function · Endocrine and hormones

    Source sentences

    Summary
    Peptides of the anterior (Lys-Glu-Asp-Gly) and posterior (Ala-Glu-Asp-Gly) thyroid lobes injected to hypophysectomized birds prevent atrophic changes of the thyroid gland, normalize immune and hemostatic parameters.
    1 context sentence
    Summary · context
    Neonatal hypophysectomy in chicken produces enlarged follicles of the thyroid gland, accumulation of colloids, impressed follicular epithelium, increased nucleus-cytoplasm ratio in thyrocytes, atrophied inter-follicular epithelium, depressed immunity, development of hypercoagulation and depressed fibrinolysis.

    In this study, Epitalon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Epitalon.

  2. 02AnimalNot a test of Epitalon aloneAnimal study (in vivo)Efficacy outcome

    In hypophysectomized birds, the injected peptides Lys-Glu-Asp-Gly and Ala-Glu-Asp-Gly normalized immune parameters.

    In plain wordsIn birds with the pituitary gland removed, the two injected peptides brought immune measures back to normal.

    Peptide
    Epitalon
    Outcome
    IncreaseImmune parameters
    Study

    chickenn: not reported in source

    Hypophysectomized chicken and one-year-old birds
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    Peptides of the anterior (Lys-Glu-Asp-Gly) and posterior (Ala-Glu-Asp-Gly) thyroid lobes injected to hypophysectomized birds prevent atrophic changes of the thyroid gland, normalize immune and hemostatic parameters.
    1 context sentence
    Summary · context
    Neonatal hypophysectomy in chicken produces enlarged follicles of the thyroid gland, accumulation of colloids, impressed follicular epithelium, increased nucleus-cytoplasm ratio in thyrocytes, atrophied inter-follicular epithelium, depressed immunity, development of hypercoagulation and depressed fibrinolysis.

    In this study, Epitalon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Epitalon.

  3. 03AnimalNot a test of Epitalon aloneAnimal study (in vivo)Efficacy outcome

    In hypophysectomized birds, the injected peptides Lys-Glu-Asp-Gly and Ala-Glu-Asp-Gly normalized hemostatic parameters.

    In plain wordsIn birds with the pituitary gland removed, the two injected peptides brought blood clotting measures back to normal.

    Peptide
    Epitalon
    Outcome
    MixedHemostatic parameters
    Study

    chickenn: not reported in source

    Hypophysectomized chicken and one-year-old birds
    Outcome group
    Bleeding and clotting · Cardiovascular

    Source sentences

    Summary
    Peptides of the anterior (Lys-Glu-Asp-Gly) and posterior (Ala-Glu-Asp-Gly) thyroid lobes injected to hypophysectomized birds prevent atrophic changes of the thyroid gland, normalize immune and hemostatic parameters.
    1 context sentence
    Summary · context
    Neonatal hypophysectomy in chicken produces enlarged follicles of the thyroid gland, accumulation of colloids, impressed follicular epithelium, increased nucleus-cytoplasm ratio in thyrocytes, atrophied inter-follicular epithelium, depressed immunity, development of hypercoagulation and depressed fibrinolysis.

    In this study, Epitalon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Epitalon.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:47 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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