In female rats, neonatal exposure to bisphenol-A at both doses increased the number of oxytocin-immunoreactive neurons in the paraventricular nucleus.
In plain wordsIn female rats, bisphenol-A exposure after birth increased the number of the body's own oxytocin-producing neurons in one brain area.
- Peptide
- Oxytocin
- Outcome
- IncreaseOxytocin-immunoreactive neurons in the paraventricular nucleus
- Study
rat (Long Evans)n: not reported in source
neonatal bisphenol-A exposure- Comparator
- Control females
- Outcome group
- Sex hormones and fertility · Endocrine and hormones
Source sentences
Both doses of BPA increased the number of OT-ir neurons within the PVN
2 context sentences(design, population, supporting numbers)
Here, using neural tissue obtained from the same animals, we explored the impact of neonatal BPA exposure on the development of sexually dimorphic hypothalamic regions critical for female reproductive physiology and behavior.
Endpoints included quantification of oxytocin-immunoreactive neurons (OT-ir) in the paraventricular nucleus (PVN), serotonin (5-HT-ir) fiber density in the ventrolateral subdivision of the ventromedial nucleus (VMNvl) as well as ERα-ir neuron number in the medial preoptic area (MPOA), the VMNvl, and…
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.