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Study · Measured the body's own peptide · 2000

2 results

Effects of steroids on endometrial oxytocin mRNA production.

Behrendt-Adam CY, Adams MH, Simpson KS, McDowell KJ

Journal of reproduction and fertility. Supplement1 Jan 2000

PMID20681141 (opens in a new tab)PepBankPUB-20681141
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In anoestrous mares, oestradiol treatment increased endometrial oxytocin mRNA abundance compared with all other groups.

    In plain wordsIn mares, oestradiol raised the body's own oxytocin gene activity in the uterine lining compared with the other groups.

    Peptide
    Oxytocin
    Outcome
    IncreaseEndometrial oxytocin mRNA abundance
    Study

    horsen = 19

    Anoestrous mares, endometrium
    Comparator
    All other groups
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Source sentences

    Summary
    Oxytocin mRNA abundance was significantly higher (P < 0.05) in the oestrogen-treated group than in all other groups.
    1 context sentence
    Summary · context
    In this study, the roles of oestrogen and progesterone in the regulation of oxytocin gene expression in equine endometrium were examined.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In anoestrous mares, progesterone for 6 or 12 days after oestradiol priming returned endometrial oxytocin mRNA to levels similar to controls.

    In plain wordsIn mares, progesterone after oestradiol brought the body's own oxytocin gene activity back to control levels.

    Peptide
    Oxytocin
    Outcome
    DecreaseEndometrial oxytocin mRNA after progesterone following oestradiol priming
    Study

    horsen: not reported in source

    Anoestrous mares, endometrium
    Comparator
    Oestradiol alone
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Source sentences

    Summary
    Progesterone treatment for either 6 or 12 days after oestradiol priming returned oxytocin mRNA abundance to levels similar to those of controls.
    1 context sentence
    Summary · context
    In this study, the roles of oestrogen and progesterone in the regulation of oxytocin gene expression in equine endometrium were examined.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:51 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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