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Study · Animal study (in vivo) · horse · 2000

3 results

The uterus as a source of oxytocin in cyclic mares.

Stout TA, Lamming GE, Allen WR

Journal of reproduction and fertility. Supplement1 Jan 2000Cited by 3 (Europe PMC)

PMID20681139 (opens in a new tab)PepBankPUB-20681139
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In mares on day 14 after ovulation, intrauterine oxytocin stimulated a large increase in peripheral plasma 13,14-dihydro-15-keto PGF2alpha concentrations.

    In plain wordsIn mares, oxytocin placed in the uterus caused a large rise in a blood marker of prostaglandin release.

    Peptide
    Oxytocin
    Outcome
    IncreasePlasma PGFM after intrauterine oxytocin
    Study

    horsen = 4

    Cyclic mares
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated · intrauterineAs given in this study (horse).

    Source sentences

    Summary
    Furthermore, intrauterine administration of oxytocin to four mares on day 14 after ovulation stimulated a large increase in peripheral plasma 13,14-dihydro-15-keto PGF2alpha concentrations without a corresponding increase in plasma oxytocin concentrations.
  2. 02AnimalAnimal study (in vivo)Pharmacokinetics

    In mares, intrauterine oxytocin was not accompanied by an increase in plasma oxytocin concentrations.

    In plain wordsIn mares, oxytocin placed in the uterus did not raise oxytocin levels in blood.

    Peptide
    Oxytocin
    Outcome
    No significant changePlasma oxytocin after intrauterine oxytocin
    Study

    horsen = 4

    Cyclic mares
    Outcome group
    Pharmacokinetics · Reproductive and sexual health
    Studied dose
    Dose not stated · intrauterineAs given in this study (horse).

    Source sentences

    Summary
    without a corresponding increase in plasma oxytocin concentrations.
    1 context sentence
    Summary · context
    Furthermore, intrauterine administration of oxytocin to four mares on day 14 after ovulation stimulated a large increase in peripheral plasma 13,14-dihydro-15-keto PGF2alpha concentrations without a corresponding increase in plasma oxytocin concentrations.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 03AnimalEndogenous levelAnimal study (in vivo)Other

    In cyclic mares on days 14-18 after ovulation, the body's own oxytocin in uterine flushings was many times higher than in peripheral plasma.

    In plain wordsIn mares, the body's own oxytocin was many times higher inside the uterus than in blood.

    Peptide
    Oxytocin
    Outcome
    IncreaseOxytocin concentration in uterine flushings versus plasma
    Study

    horsen = 9

    Cyclic mares
    Comparator
    Peripheral plasma
    Outcome group
    Hormone levels · Reproductive and sexual health

    Source sentences

    Summary
    In the present study, measurement of oxytocin concentrations in uterine flushings recovered from nine mares during days 14-18 after ovulation gave values that were many times higher than those measured concurrently in peripheral plasma.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:51 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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