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Study · Not a test of the peptide alone · 2010

2 results

Effect of PEGylation on stability of peptide in poly(lactide-co-glycolide) microspheres.

Park EJ, Tak TH, Na DH, Lee KC

Archives of pharmacal research27 Jul 2010Cited by 12 (Europe PMC)

PMID20661722 (opens in a new tab)DOI10.1007/s12272-010-0718-z (opens in a new tab)PepBankPUB-20661722
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking GHRP-6.

  1. 01LabNot a test of GHRP-6 aloneIn vitro (cell-free)Other

    In lab tests, native GHRP‑6 in PLGA microspheres formed several acylated peptides during one month of incubation in buffer.

    In plain wordsIn lab tests, GHRP‑6 inside PLGA microspheres was chemically altered by the microsphere material over one month.

    Peptide
    GHRP-6
    Outcome
    Not applicableAcylation of native GHRP-6 in PLGA microspheres
    Study

    n: not reported in source

    PLGA microspheres in phosphate buffer, 37 degrees C
    Outcome group
    Formulation, delivery and stability · Pharmacology

    Source sentences

    Summary
    During incubation in a 0.1 M phosphate buffer (pH 7.4) for one month at 37 degrees C, native GHRP-6 microspheres were identified to form several acylated peptides by reversed-phase HPLC and MALDI-TOF MS
    1 context sentence
    Summary · context
    The microspheres encapsulating native GHRP-6 or mono-PEG-GHRP-6 were prepared using the single oil-in-water emulsion solvent evaporation method.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

  2. 02LabNot a test of GHRP-6 aloneIn vitro (cell-free)Other

    In lab tests, mono-PEG-GHRP‑6 in PLGA microspheres was not affected by peptide acylation during one month of incubation, unlike native GHRP‑6.

    In plain wordsIn lab tests, PEG-linked GHRP‑6 in microspheres was not chemically altered, unlike plain GHRP‑6.

    Peptide
    GHRP-6
    Outcome
    No significant changeAcylation of PEGylated GHRP-6 in PLGA microspheres
    Study

    n: not reported in source

    PLGA microspheres in phosphate buffer, 37 degrees C
    Comparator
    Native GHRP-6 microspheres
    Outcome group
    Formulation, delivery and stability · Pharmacology

    Source sentences

    Summary
    whereas the mono-PEG-GHRP-6 microspheres was not affected from peptide acylation by PLGA.
    1 context sentence
    Summary · context
    The microspheres encapsulating native GHRP-6 or mono-PEG-GHRP-6 were prepared using the single oil-in-water emulsion solvent evaporation method.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 12:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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